Successful use of Etanercept for the treatment of Reiter’s syndrome: a case report and review of the literature

Edrees, Amr

doi:10.1007/s00296-011-2000-1

Cited by 23 publications

(13 citation statements)

References 15 publications

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“…Sabirli et al [9] mean score of KOOS all subscales were less than present study results but trend is similar between the two studies meaning sports and recreation subscale is the least followed by QOL subscale and symptom subscale was the maximum in both studies.…”

Section: Discussionsupporting

confidence: 69%

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Correlation of Self-Reported Questionnaire (KOOS) with Some Objective Measures in Primary OA Knee Patients

2014

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Purpose. Objective of the present study was to see the correlation of subjectively measured KOOS questionnaire with objectively measured 6-minute walk test (6-MWT), age, height, weight, and BMI. Participants. 251 subjects with OA knee based on American College of Rheumatology criteria. Methods. After passing inclusion and exclusion criteria, the following parameters were recorded: age, height, weight, and BMI. Then subjects were asked to fill KOOS questionnaire; then all subjects were asked to do self-paced walk for 6 minutes. Analysis. Spearman rank test was done to see the correlation. Significant level was set at P < 0.05. Results. 6-MWT had a weak correlation with KOOS-ADL (rho 0.461) and strong correlation with KOOS-symptom, KOOS-pain, and KOOS-sports and very strong correlation with KOOS-QOL. BMI had a strong correlation with KOOS-pain, KOOS-symptom, KOOS-ADL, and KOOS-sports and very strong correlation with KOOS-QOL. Weight had a weak correlation with KOOS-symptom, KOOS-ADL, and KOOS-sports and strong correlation with KOOS-pain and KOOS-QOL. All the above values were significant with P < 0.001. Conclusion. KOOS is strongly positively correlated with 6-MWT and negatively correlated with BMI. Its correlation strength has decreased with weight.

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Section: Discussionsupporting

confidence: 69%

“…In previous studies, WOMAC, SF-36, and KOOS are compared with timed up and go (TUG) test [7, 9–11]. However there is no study that compares self-reported questionnaire with 6-MWT which is more deals with ADL as this measures both walking ability as well as endurance.…”

Section: Introductionmentioning

confidence: 99%

Correlation of Self-Reported Questionnaire (KOOS) with Some Objective Measures in Primary OA Knee Patients

2014

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“…Other drugs that may be used includes etanercept, infliximab, sulfasalazine,methotrexate, and azathioprine (Wu and Schwartz, 2008;Edrees, 2012;Hughes and Keat, 1994;Berenbaum et al, 1996;Youssef et al, 1992;Gill and Majithia, 2008).…”

Section: Discussionmentioning

confidence: 99%

“…It is typically identified in young male patients during their third or fourth decade of life after a urogenital or gastrointestinal infection (Howard et al, 2007;Wu and Schwartz, 2008). A significant number of patients with Reiter's syndrome also manifest their mucocutaneous symptoms, namely keratoderma blennorrhagica on the palms and soles, onychodystrophy, oral ulcers, and circinate balanitis (Edrees, 2012). These clinical features are necessary for establishing a diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Reiters syndrome presenting with lumbar and leg pain as the chief complaint: A case report and literature review

Liu¹,

Miao²,

Lian³

et al. 2014

Sci. Res. Essays

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Reiter's syndrome is usually known as a clinical triad of arthritis, urethritis, and conjunctivitis. Peripheral nerve involvement in Reiter's syndrome is extremely rare. We report here on a 36-year-old man presenting to the orthopedic department with a chief complaint of lumbar and leg pain who initially was found to have lumbar intervertebral disc and was diagnosed as Reiter's syndrome 3 months later. Human leukocyte antigen (HLA)-B27 test and bacterial culture of urine were positive. Clinical symptoms were relieved after conservative treatment with celecoxib, dexamethasone and antibiotics. This case suggests that Reiter's syndrome can present as lumbar spine lesions and should be considered in the differential diagnosis of lumbar intervertebral disc.

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“…Sulfasalazine has been used successfully in chronic cases of reactive arthritis, and early introduction (<3 months) has been shown to be more effective than placebo in inducing remission [53]. There are case reports regarding the successful use of anti-TNF therapy in cases not responding to conventional therapy, particularly in HLA-B27 positive patients [54]. …”

Section: Treatment and Outcomementioning

confidence: 99%

The Role of Intracellular Organisms in the Pathogenesis of Inflammatory Arthritis

Singh

Karrar

2014

International Journal of Inflammation

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Inflammatory arthritis is a condition which is characterised by recurrent episodes of joint pain and swelling. It encompasses a spectrum of disorders ranging from rheumatoid arthritis to ankylosing spondylitis. In these conditions, for reasons that are poorly understood, the immune system raises an inflammatory response within the joint space. In some cases, autoantigens have been identified (e.g., anticitrullinated peptides in rheumatoid arthritis), but the absence of these, in the seronegative arthritides, for example, raises question as to the underlying pathogenesis. Interest has, therefore, turned to host-pathogen interactions and whether aberrant immune responses to these could explain the development of arthritis. This has been most widely studied in reactive arthritis (ReA), where an infectious episode precedes the development of the joint symptoms. In this review, we present the evidence for the role of host-bacterial interactions in the pathogenesis of joint inflammation with particular emphasis on ReA. We discuss a range of possible mechanisms including molecular mimicry, persistent low grade infections, and abnormal host responses to common bacterial causes of reactive arthritis as well as discussing some of the clinical challenges that we face in making the diagnosis and in treatment of persistent symptoms.

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Successful use of Etanercept for the treatment of Reiter’s syndrome: a case report and review of the literature

Cited by 23 publications

References 15 publications

Correlation of Self-Reported Questionnaire (KOOS) with Some Objective Measures in Primary OA Knee Patients

Correlation of Self-Reported Questionnaire (KOOS) with Some Objective Measures in Primary OA Knee Patients

Reiters syndrome presenting with lumbar and leg pain as the chief complaint: A case report and literature review

The Role of Intracellular Organisms in the Pathogenesis of Inflammatory Arthritis

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