1983
DOI: 10.1213/00000539-198307000-00002
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Succinylcholine-Induced Increases in Plasma Catecholamine Levels in Humans

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Cited by 31 publications
(9 citation statements)
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“…However, cisatracurium has no effect on catecholamines, and succinylcholine has a brief, catecholamine- releasing effect that may contribute, at most, to catecholamine increase at the time of intubation but not at later time-points. 27,28 Hence, smaller stress responses in PLMA™ patients do not appear to be accounted for by chronic therapies or anesthesia drugs. Rather, we believe they result from features of airway devices.…”
Section: Discussionmentioning
confidence: 99%
“…However, cisatracurium has no effect on catecholamines, and succinylcholine has a brief, catecholamine- releasing effect that may contribute, at most, to catecholamine increase at the time of intubation but not at later time-points. 27,28 Hence, smaller stress responses in PLMA™ patients do not appear to be accounted for by chronic therapies or anesthesia drugs. Rather, we believe they result from features of airway devices.…”
Section: Discussionmentioning
confidence: 99%
“…15 In man, the observed increases in blood pressure after laryngoscopy and intubation are accompanied by an increase in plasma norepinephrine concentrations, suggesting increased sympathetic activity. [16][17][18][19] Present study With our study design, we were not able to examine the effects of each single intervention. Instead, we wanted to mimic the daily clinical routine by monitoring the cumu]ative haemodynamic changes following a series of both pharmacological and mechanical interventions.…”
Section: Discussionmentioning
confidence: 99%
“…Suxamethonium increases heart rate considerably via sympathetic stimulation. A marked increase in a patient's plasma concentration of norepinephrine was seen following suxamethonium [24]. We therefore anticipated, in the present study, that landiolol would suppress the increase in plasma norepinephrine level and, hence, prevent the heart rate from increasing after an injection of suxamethonium.…”
Section: Discussionmentioning
confidence: 74%