Glass-lined tanks/reactors provided
with a torispherical (dish)
bottom and equipped with a retreat-blade impeller (RBI) are commonly
used in the industrial syntheses of Active Pharmaceutical Ingredients
(APIs). The power, P, dissipated by the RBI in the
liquid in the tank is critical to many mixing processes, especially
since the power per unit liquid volume, P/V, controls many mixing phenomena. Despite their common
industrial use, limited information on P for RBIs
and the corresponding nondimensional Power number, Po, is available. Here, P values for an RBI in liquids
of very different viscosities at different agitation speeds and for
different baffling configurations, i.e., unbaffled, partially baffled
(with a single “beavertail” baffle), and fully baffled
(four rectangular baffles), were measured experimentally in a scaled-down
version of a typical reactor for API synthesis. The corresponding Po values were obtained for a large range of the Reynolds
number, Re (1 < Re < 400,000).
Po
was found to vary significantly with
baffling type and Re. Equations correlating Po with Re and baffling type are presented.