Sudden death involving inhalation of 1,1-difluoroethane (HFC-152a) with spray cleaner: Three case reports

Sakai, Kentaro; Maruyama-Maebashi, Kyoko; Takatsu, Akihiro; Fukui, Kenji; Nagai, Tatsuo; Aoyagi, Miwako; Ochiai, Eriko; Iwadate, Kimiharu

doi:10.1016/j.forsciint.2010.08.026

Cited by 33 publications

(9 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mechanism of a halogenated gas associated arrhythmia has been shown in animal studies to be sensitization of the myocardium to catecholemines, probably due to the halogenated hydrocarbon moeity of DFE. [5,6] Inhalation abuse can cause angioedema 3 . If a tightly fitting bag is placed over the head with huffing, anoxia can result .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Case Report: Cold thermal injury and syncope from pressurized dust cleaning spray

Espinosa¹

2022

AMCRCS

View full text Add to dashboard Cite

Here we present the case of a 21-year -old patient who huffed pressurized dust cleaning spray with subsequent syncope and cold thermal injury to her hands. Air spray cleaners contain halogenated gas, which serves as a propellent to blow dust from electrical and computer devices. The halogenated compound can cause euphoria and can be used as an inhaled abused substance. Use of such substances can be associated with syncope, sudden death, hypoxia and cold thermal injuries. Airway swelling has been reported. Orofacial and digital frostbite has been described as a clue to the detection of the use of such inhalants. An awareness of the association of halogenated gas with syncope and of the possibility of cold thermal injury can be very useful to the clinician.

show abstract

Section: Discussionmentioning

confidence: 99%

“…This compound has been associated with syncope, arrhythmias and even sudden death. [3,5] The results can include significant morbidity and even mortality. Two associated medical problems are discussed in this case-syncope and cold thermal injury.…”

Section: Introductionmentioning

confidence: 99%

Case Report: Cold thermal injury and syncope from pressurized dust cleaning spray

Espinosa¹

2022

AMCRCS

View full text Add to dashboard Cite

show abstract

“…Despite prior reports of sudden death, no definitive rhythm documentation has been published. 1 , 2 , 3 Tetrafluoroethane is used as a propellant for wine cork removers and gas dusters, whose intended use is to remove debris and dust particles from computer keyboards. These products are not FDA regulated and are widely available.…”

Section: Discussionmentioning

confidence: 99%

Huffing and twist: Fatal Torsade de pointes associated with Tetrafluoroethane Inhalation and amphetamine use

Burke

Haigney

Farasat

et al. 2021

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

“…This patient was noted to have significant hepatic and renal injury, similar to our patient. Life threatening arrhythmias including ventricular fibrillation causing sudden cardiac death has been reported previously[ 6 - 8 ]. Toxic myopericarditis have been previously diagnosed in these patients[ 2 ].…”

Section: Discussionmentioning

confidence: 99%

Cardiac involvement in hydrocarbon inhalant toxicity — role of cardiac magnetic resonance imaging: A case report

Jolly¹,

Davis²,

Ali³

et al. 2021

WJC

View full text Add to dashboard Cite

BACKGROUND We report a patient who was diagnosed with toxic myopericarditis secondary to hydrocarbon abuse using cardiac magnetic resonance imaging (CMR). CASE SUMMARY A 25-year-old male presented to emergency department with chest pain for 3 d. Patient also reported sniffing hydrocarbon containing inhalant for the last 1 year. Labs showed elevated troponin and electrocardiography was suggestive of acute pericarditis. Echocardiogram showed left ventricular (LV) ejection fraction (EF) of 40%. Given patient’s troponin elevation and reduced EF, cardiac catheterization was performed which showed normal coronaries. CMR was performed for myocardial infarction with non-obstructive coronary arteries evaluation. CMR showed borderline LV function with edema in mid and apical LV suggestive of myocarditis. CONCLUSION CMR can be used to diagnose toxic myopericarditis secondary to hydrocarbon abuse.

show abstract

Sudden death involving inhalation of 1,1-difluoroethane (HFC-152a) with spray cleaner: Three case reports

Cited by 33 publications

References 27 publications

Case Report: Cold thermal injury and syncope from pressurized dust cleaning spray

Case Report: Cold thermal injury and syncope from pressurized dust cleaning spray

Huffing and twist: Fatal Torsade de pointes associated with Tetrafluoroethane Inhalation and amphetamine use

Cardiac involvement in hydrocarbon inhalant toxicity — role of cardiac magnetic resonance imaging: A case report

Contact Info

Product

Resources

About