Sudden Hearing Loss in a Cyclosporin-Treated Renal Transplantation Patient

Neurologic complications of liver transplantation in adults

“…This has not been reported previously in adult liver transplantation. Deafness has occurred in pediatric patients undergoing liver transplantation 41 and has previously been reported in association with both tacrolimus and cyclosporine, 42,43 although both cases were in renal transplant recipients. With our retrospective study design, it is difficult to know why these patients developed this complication.…”

A Case of Sudden Deafness Probably Due to Antithymocyte Globulin Treatment

“…Sudden hearing loss due to ciclosporininduced thromboembolic complications was reported in renal transplant patients [7], In our case, ciclosporin therapy was terminated be fore sudden hearing loss occurred, so ciclos porin may be excluded as the causative agent. Onset of the sudden hearing loss in the pre sent case was on the 2nd day o f the ATG ther apy and began to improve on the 11th day after terminating ATG.…”

Role of ciclosporin in steroid-responsive sudden sensorineural hearing loss

“…Behçet's syndrome is known to be associated with an increased incidence of SNHL and treatment with ciclosporin has been proven to improve hearing in up to 25% of patients [12]. This conflicts with two case reports [13,14] in which ciclosporin was cited as a causal factor in SNHL; however, both of these involved renal transplant patients. The proposed mechanism was a possible thromboembolic event induced by ciclosporin therapy.…”