Sugammadex Allows Fast-Track Bariatric Surgery

Carron, Michele; Veronese, S.; Foletto, Mirto; Ori, Carlo

doi:10.1007/s11695-013-0926-y

Cited by 73 publications

(68 citation statements)

References 34 publications

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“…It appears that patients who were in deep NMB did not have enough adverse reactions for the anaesthetist to administer additional doses of the aforementioned medications. As opposed to Carron et al (19), our study clearly shows a reduction of operative time (laparascopic and total). This can be attributed to the 6 patients with moderate NMB, with bad working conditions.…”

Section: Discussioncontrasting

confidence: 98%

Neuromuscular Blockade, Bariatric Surgeon Satisfaction, and Quality of Patient Recovery

Garneau

Garofalo

Deslauriers

et al. 2017

J Minim Invasive Surg Sci

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Background: To date, little is known about neuromuscular blockade (NMB) and its impact in bariatric surgery and patient recovery. The goal of this study was to better assess the relationship between depth of NMB, bariatric surgeon's satisfaction, and the quality of patient recovery. Methods: Between January and September 2015, we did a prospective observational study of 50 morbidly obese patients undergoing elective laparoscopic sleeve gastrectomy (LSG) under general anesthesia at our ambulatory surgical center. Rocuronium was used for tracheal intubation with bolus doses to maintain NMB. NMB was monitored at 5 minute intervals during the surgery, and at 30 second intervals following the reversal agent. The surgeon was blind to all anesthesia procedures and scored the surgical working conditions at 15 min intervals. Demographic data, operative data, and conditions were analyzed.

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Section: Discussioncontrasting

confidence: 98%

Neuromuscular Blockade, Bariatric Surgeon Satisfaction, and Quality of Patient Recovery

Garneau

Garofalo

Deslauriers

et al. 2017

J Minim Invasive Surg Sci

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“…It is generally recommended to administer sugammadex according to the body weight [31]. In contrast, Loupec et al [32] advocate that in morbidly obese patients, 4 mgkg -1 sugammadex using ideal body weight provides satisfactory reversal of deep rocuronium-induced NMB.…”

Section: Obese Patientsmentioning

confidence: 99%

A Short Update on Sugammadex with a Special Focus on Economic Assessment of its Use in North America

Zaouter¹,

Mion²,

Palomba³

et al. 2017

J Anesth Clin Res

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Sugammadex offers significant advantages over the current anticholinesterase reversal drugs. Sugammadex used has been approved for the United Stated and for Canada since December 2015 and February 2016, respectively. The present article aims to provide a straightforward and concise review of the most recent literature describing its clinical advantages in routine use. A thorough and cost-effective evaluation has been conducted specifically for North America to determine if its price justifies its inclusion into regular patients' care. The search examined the relevant literature from January 2013 to October 2016. The present narrative review describes how sugammadex could play a crucial role in the modern conduct of anesthesia. The particular emphasis on sugammadex cost-effective analysis performed in this article suggests that this new reversal agent should be considered for a wider use in North America.

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“…Muscle relaxants have also been dosed using ideal body weight; hovewer, recent publications using sugammadex for muscle relaxant reversal show that even doses for total body weight can be used without prolonging the procedure. [27] Due to these controversies of intravenous dosing, some authors suggest that using inhalational anesthesia results in faster awakening. [28] If total intravenous anesthesia is to be chosen, continuous monitorization with BIS (bispectral index) and using TCI (target controlled infusion) might be an option.…”

Section: Intraoperative Management Of the Morbidly Obese Patientmentioning

confidence: 99%

“…[26] Several modalities have been used to prolong the safe duration of apnea. [27] Another study has revealed that single lung ventilation in the morbidly obese is also possible if surgical and anesthesia teams work together and provide oxygenation breaks as needed. [28] Since fat tissue increases much more than lean tissue, morbidly obese individuals are relatively hypovolemic and anesthesia induction with acute vasodilation may cause acute or serious hypotension.…”

Section: Intraoperative Management Of the Morbidly Obese Patientmentioning

confidence: 99%

Anesthesia for the surgical procedures of the morbidly obese

Pamuk¹

2017

Laparosc Endosc Surg Sci

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Surgery for the morbidly obese is no longer a novelty. Understanding the basic mechanisms of the pathophysiology of morbid obesity and taking simple precautions while preparing these patients for surgery will help reduce complications. This review outlined preoperative, perioperative, and postoperative management of the morbidly obese patient in line with the current knowledge. Airway management, drug choices, changes in respiratory, circulatory, urinary, and metabolic systems were discussed. Some early and long-term changes in the morbidly obese, like gastroesophageal reflux and vitamin deficiencies were also summarized to aid in subsequent operations and management.

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Sugammadex Allows Fast-Track Bariatric Surgery

Abstract: Sugammadex allowed a safer and faster recovery from profound rocuronium-induced NMB than neostigmine did in patients with MO. Sugammadex may play an important role in fast-track bariatric anesthesia.

Cited by 73 publications

References 34 publications

Neuromuscular Blockade, Bariatric Surgeon Satisfaction, and Quality of Patient Recovery

Neuromuscular Blockade, Bariatric Surgeon Satisfaction, and Quality of Patient Recovery

A Short Update on Sugammadex with a Special Focus on Economic Assessment of its Use in North America

Anesthesia for the surgical procedures of the morbidly obese

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