Suitability of commercial colloids for magnetic hyperthermia

Long‐Term Stability and Reproducibility of Magnetic Colloids Are Key Issues for Steady Values of Specific Power Absorption over Time

“…[47] Kallumadil et al published the relationship between ILP and hydrodynamic diameter indicating an optimum value to heat generation around 70 nm. [35] According with this affirmation the SPA values should be decreased with the increment of DH, but they are invariable with time as could be observed in our case. The as prepared samples showed DH values around 200 nm, which remained essentially unchanged during the first 2-3 months after preparation.…”

“…[35][36] The product A*B represents the initial heat rate and can be used to obtain the SPA from the derivative of Eq. 6…”

“…For fitting this behaviour, a linear function is usually used [30] but also a Box-Lucas function has been proposed to extract the SPA values. [35,37] The initial increase of temperature can be extracted from (dT/dt)max so that a standardized protocol for calculating the SPA can be given.…”

“…A parameter named intrinsic loss power (ILP=SPA/(f·H 2 ) has been proposed by Kallumadil and co-workers [35] as a tentative to define an instrument-independent parameter designed to compare measurements under different amplitude and frequency conditions. As discussed above, the SPA(H,f) has not the assumed quadratic (H) and linear (f) dependences and thus the ILP approximation is expected to fail under the usual laboratory conditions.…”

Core–shell La 1− x Sr x MnO 3 nanoparticles as colloidal mediators for magnetic fluid hyperthermia

“…Various aspects of the method have been widely discussed in a number of articles, e.g. Andrä (1998), Hergt et al (2002), Kallumadil et al (2009), Mornet et al (2004Mornet et al ( , 2006 and Pankhurst et al (2003Pankhurst et al ( , 2009. The concept of the treatment is based on the higher heat sensitivity of tumour cells in comparison with healthy tissue.…”