Sulfadiazine hosted in MIL-53(Al) as a biocide topical delivery system

Abstract

<p>Sulfadiazine (SDZ), a bacteriostatic agent, was hosted in MIL-53(Al) and modified-zinc MIL-53(Al,Zn).</p>

Copper(ii)-MOFs for bio-applications

“…Guo et al show the improved efficiency for wound healing by applying a MOF-Cu, as an antibacterial alternative with a long-acting effect and in vivo healing of wounds infected by bacteria 106,111 and in vivo wound evaluations have also been reported in mice. 119,120 In this same concept of application at the site of action, but now on inanimate surfaces, we can mention the use of copper-based MOFs in biofilms, for which Wang proposes a study with a dye called SYTO-9, which stains viable bacteria green and dead bacteria red with a dye called PI tested in biofilms. 121 Another study reported by Skvortsova et al shows high catalytic activity and antimicrobial properties of the surface of the MOF (Cu-BTC) related to the high surface area, 122 and in the same way the catalyzed release of nitric oxide is proposed.…”

CYCU-3: an Al(iii)-based MOF for SO2 capture and detection

“…15 Based on their remarkable properties, MOFs have been widely applied in different research fields, particularly catalysis, 16 adsorption of pollutants, 17 detection, 18 and drug delivery. 19 In the case of SO 2 removal, MOFs that have been successfully implemented feature high chemical stability toward SO 2 and ideally participate in SO 2 physisorption processes, 20 since, in some cases, metal–oxygen bonds can dissociate after SO 2 adsorption. For example, although MOF-177 holds the SO 2 uptake record (25.7 mmol g −1 at 298 K and 1 bar), after SO 2 adsorption, the crystal structure collapses.…”

Adsorption and Release of Sulfamethizole from Mesoporous Silica Nanoparticles Functionalised with Triethylenetetramine

“…Ghedini et al studied a DDS for the controlled release of silver sulphadiazine for topical administration from hybrid gels using chitosan and silica as precursors [ 41 ]. Recently, Rosas et al studied the release of the same compound from MIL-53(Al) MOFs reaching up to 80% release in physiological conditions [ 42 ]. Suman et al reported the impregnation of silver sulphadiazine on SBA-15 mesoporous silica reaching a 95% release in simulated body fluid after 48 h [ 43 ].…”