Sulfadimethoxine Degradation Kinetics in Manure as Affected by Initial Concentration, Moisture, and Temperature

Abstract

Sulfadimethoxine is a widely used sulfonamide veterinary antibiotic and could be a source of agricultural contamination. Therefore, information is needed about its degradation kinetics in manure under aerobic conditions. Based on the analysis of first-order kinetics and the assumption that sulfadimethoxine availability for degradation in manure could be limiting, a new kinetic model was developed and was found to fit the degradation kinetics well. The degradation rate in sterile manure was found to be much lower than in nonsterile manure, indicating that biodegradation was significant. In biologically active manure, the degradation rate constant decreased with increasing initial concentration of sulfadimethoxine, implying that the activity of the degrading microorganisms was inhibited. Increasing moisture or temperature was found to increase sulfadimethoxine degradation in manure. Mixing manure containing high levels of sulfadimethoxine with manure containing lower levels may result in more rapid degradation, thus greatly diminishing sulfadimethoxine contamination in manure and significantly reducing sulfadimethoxine inputs into the environment. During treatment, keeping the manure moist and storing in a moderately warm place under aerobic conditions may also help to diminish sulfadimethoxine contamination.

Influence of moisture on the availability and persistence of clotrimazole and fluconazole in sludge-amended soil

“…The obtained data showed a faster dissipation rate of clotrimazole at higher soil moisture contents, whereas for fluconazole no significant differences were observed (Table 4). These data are in agreement with the results reported for other organic compounds when soil moisture content was taken into account [21][22][23]. The influence of soil moisture content in the dissipation of organic compounds could be explained by their desorption from soil, which is smaller in dry soils than in wet soils, as pointed out previously [24].…”

Biological degradation and microbial function effect of norfloxacin in a soil under different conditions

“…Similar dissipation behavior was also observed for other antibiotics such as sulfadiazine and oxytetracycline in soils. [5,6,11,12] Sulfadiazine was reported to bind irreversibly with soil organic matter. [12,26] Yang et al [11] also suggested that strong sorption of oxytetracycline onto soil during the incubation period could lead to a decrease in its recovery from the soil.…”

“…[5][6][7][8][9][10][11][12] The influencing factors investigated so far include chemical concentration, [5,6,11,12] moisture and temperature, [5,6] manure amendment [5,6,10] and soil properties. [10][11][12] Accinelli et al [10] studied the environmental fate of two sulfonamide antibiotics (sulfamethazine and sulfachloropyridine) in soils and found that the sulfonamides dissipated more rapidly in the silt loam soil than in the sandy soil.…”

Leaching potential of nonsteroidal anti-inflammatory drugs in soils

“…However, soils in the packed columns were always saturated with water, so greater quantities of chemicals were dissolved in the soil water of the saturated soil and were more bioavailable to microbial degradation. Increasing moisture has been found to increase the degradation of pesticides and other chemicals in soils [35,36]. In the calculations described above, we probably underestimated the degradation of NSAIDs in the soil columns.…”