2012
DOI: 10.1016/j.cgh.2011.09.027
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Sulfasalazine Crystalluria-Induced Anuric Renal Failure

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Cited by 20 publications
(5 citation statements)
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“…Although sulfasalazine is generally considered as a safe medication [2], several cases of renal injury have been reported with sulfasalazine administration [3][4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%
“…Although sulfasalazine is generally considered as a safe medication [2], several cases of renal injury have been reported with sulfasalazine administration [3][4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%
“…15 Most adverse reactions to sulfasalazine involved the hematopoietic system (75%), followed by hepatic (15%) and dermatologic (11%) issues. 15 Although interstitial nephritis, 18-20 nephrolithiasis, 21,22 and renal tubular acidosis 23 have been reported for sulfasalazine, the lack of association of sulfasalazine with renal complications in largescale studies suggests that sulfasalazine-induced kidney injury is potentially under-reported or underrecognized.…”
Section: Discussionmentioning
confidence: 99%
“…41 These drugs are associated with unwanted effects on male fertility along with adverse effect of sulfasalazine including vomiting, hypospermia, hepatitis, pneumonitis, hemolytic anemia and chronic nephrosis andencephalitis. 42,43 It has been observed that sometimes treatment with sulfasalazine exacerbates colitis which results in diarrhea, abdominal cramps and uneasiness. 44 These side effects can be overcome by medicinal plant based therapeutics which could have less or no adverse side effects.…”
Section: Protection Against Ulcerative Colitismentioning
confidence: 99%