Sunscreens and Photocarcinogenesis: An Objective Assessment

Nutraceuticals and Cancer

“…Chemical sunscreens act by filtering UV transmission to the epidermis and dermis of skin (Wolf 2003). The most widely used photon absorbing agents are para-aminobenzoic acid (PABA), PABA esters, benzophenones, dibenzomethanes, salicylates and cinnamates (Elmets and Anderson 1996). This effectiveness is measured in the SPF of a sunscreen which is an experimentally derived number.…”

Carcinogenesis Induced by UV and Ionizing Radiation

“…Furthermore, the prevention of photocarcinogenesis, especially, the induction of non melanoma skin cancers, can be achieved by chemical protection using sunscreens, retinoids and indomethacon and by lowering the dietary fat supply (Agarwalaand Mukhar 1996). However, the effectiveness of these treatments against the induction of melanomais still a matter of discussion (Elmets and Anderson 1996).…”

Integrative approach in prevention and therapy of basal cellular carcinoma by association of three actives loaded into lipid nanocarriers

“…In order to protect the skin from the deleterious effects of UV radiation, sunscreen agents are used to aid the body's natural defence mechanism by absorbing, reflecting or scattering the UV rays [9]. Even though, initially sunscreen formulations were developed to prevent sunburns, today they are medical advised for skin cancer prevention by limiting at skin level the deoxyribonucleic acid (DNA) damage produced by UV radiation, directly or indirectly through reactive oxygen species (ROS) [10,11].…”