Supercritical Carbon Dioxide Extraction of Essential Oils from <i>Perovskia atriplicifolia</i> Benth.

Pourmortazavi, Seied Mahdi; Sefidkon, Fatemeh; Hosseini, Seyed Ghorban

doi:10.1021/jf0341619

Cited by 56 publications

(27 citation statements)

References 30 publications

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“…For volatile oil extraction through SC CO 2 , small changes in temperature can cause significant changes in solubility with a non-linear relationship [156]. Whereas the operative pressure is the main parameter that influences the fluid density and therefore the solvent power of supercritical fluid, the effect of temperature depends on the nature of plant material and has to be determined case by case [157].…”

Section: Process Considerationsmentioning

confidence: 99%

“…Studies about the effects of co-solvents at constant pressure and temperature evaluated the extraction efficiency of different modifiers at increasing percentages for volatile oil extractions. The addition of methanol, ethanol or halogenated co-solvents reduces the number of extracted terpenes with respect to pure SC CO 2 for Perovskia atriplicifolia but increases the extraction selectivity [157]. However, the use of co-solvents, especially at high percentages, leads to a biphasic system that will change the critical parameters of the mixture.…”

Section: Process Considerationsmentioning

confidence: 99%

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Supercritical Fluid Extraction of Plant Flavors and Fragrances

2013

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Supercritical fluid extraction (SFE) of plant material with solvents like CO 2 , propane, butane, or ethylene is a topic of growing interest. SFE allows the processing of plant material at low temperatures, hence limiting thermal degradation, and avoids the use of toxic solvents. Although today SFE is mainly used for decaffeination of coffee and tea as well as production of hop extracts on a large scale, there is also a growing interest in this extraction method for other industrial applications operating at different scales. In this review we update the literature data on SFE technology, with particular reference to flavors and fragrance, by comparing traditional extraction techniques of some industrial medicinal and aromatic crops with SFE. Moreover, we describe the biological activity of SFE extracts by describing their insecticidal, acaricidal, antimycotic, antimicrobial, cytotoxic and antioxidant properties. Finally, we discuss the process modelling, mass-transfer mechanisms, kinetics parameters and thermodynamic by giving an overview of SFE potential in the flavors and fragrances arena.

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Section: Process Considerationsmentioning

confidence: 99%

Section: Process Considerationsmentioning

confidence: 99%

Supercritical Fluid Extraction of Plant Flavors and Fragrances

2013

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“…The small lavender flowers have a sweet flavor and may be eaten in salads or used as a garnish. This species is also suitable for use in forming a decorative hedge of moderate height (Pourmortazavi, 2003). It is a favorite aromatic shrub for honey bees, with the honey made by bees fed on this shrub being colorless and having a typical flavor and aroma.…”

Section: Introductionmentioning

confidence: 99%

“…The supercritical fluid extraction (SFE) of the aerial parts of P. atriplicifolia has also been studied with the major components of SFE extracts being 1,8-cineol limonene, camphor, b-caryophyllene, d-cadinene, a-pinene, and a-terpinyl acetate (Pourmortazavi, 2003). Furthermore, in their studies, the main constituents of the same oil obtained by steam distillation were found to be 1,8-cineol camphene, and a-humulene (Pourmortazavi, 2003).…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Biological Activity of the Essential Oil ofPerovskia atriplicifolia. from Pakistan

Erdemgil

İlhan

Korkmaz

et al. 2007

Pharmaceutical Biology

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The current study describes the phytochemical profile, antimicrobial, mutagenic, and antimutagenic activity of Perovskia atriplicifolia Benth. essential oil, collected in Pakistan. The sample of essential oil was obtained from aerial parts of the plant by hydrodistillation and analyzed by gas chromatography-mass spectrometry. From the 18 compounds identified, the major compounds were camphor (28.91%), limonene (16.72%), a-globulol (10.21%), trans-caryophyllene (9.30%), and a-humulene (9.25%). Antimicrobial activity of the oil was evaluated using agar diffusion method and agar dilution method. The antimicrobial test results showed that the oil had a significant potential antimicrobial activity against 10 bacteria and 5 fungal strains. Furthermore, the mutagenic and antimutagenic activity of the oil was investigated through the Salmonella=microsome test system, with and without S9 metabolic fraction in Salmonella typhimurium TA98 and TA100. None of the tested concentrations of oil was found mutagenic. However, all tested concentrations did show an increase in antimutagenic activity with or without S9 fraction against 2-aminofluorene and daunomicina, but not sodium azide. Results presented here suggest that the essential oil of P. atriplicifolia possesses antimicrobial properties and is therefore a potential source of antimicrobial ingredients for the food and pharmaceutical industry. In addition, that it also has antimutagenic activity raises the importance of this essential oil in this area.

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“…Extracts of different compositions can be obtained by different extraction methods applied to natural products (20)(21)(22)(23)(24). The GC-MS profile of the ethyl acetate extract is shown in Figure 2.…”

Section: Gas Chromatography-mass Spectrometrymentioning

confidence: 99%

Cytotoxicity of Marchantia convoluta leaf extracts to human liver and lung cancer cells

Xiao

Chen

Zhang

et al. 2006

Braz J Med Biol Res

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The cytotoxicity of three extracts (petroleum ether, ethyl acetate and n-butanol) from a plant used in folk medicine, Marchantia convoluta, to human non-small cell lung carcinoma (H1299) and liver carcinoma (HepG2) cell lines was tested. After 72-h incubation of lung and liver cancer cell cultures with varying concentrations of extracts (15 to 200 µg/mL), cytotoxicity was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and reported in terms of cell viability. The extracts that showed a significant cytotoxicity were subjected to gas chromatography-mass spectrometry analysis to identify the components. The ethyl acetate, but not the petroleum ether or n-butanol extract, had a significant cytotoxicity against lung and liver carcinoma cells with IC 50 values of 100 and 30 µg/mL, respectively. A high concentration of ethyl acetate extract (100 µg/mL) rapidly reduced the number of H1299 cells. At lower concentrations of ethyl acetate extract (15, 30, and 40 µg/mL), the numbers of HepG2 cells started to decrease markedly. Gas chromatography-mass spectrometry analysis of the ethyl acetate extract revealed the presence of several compounds such as phytol (23.42%), 1,2,4-tripropylbenzene (13.09%), 9-cedranone (12.75%), ledene oxide (7.22%), caryophyllene (1.82%), and caryophyllene oxide (1.15%). HPLC analysis result showed that there were no flavonoids in ethyl acetate extract, but flavonoids are abundant in n-butanol extract. Further studies are needed regarding the identification, toxicity, and mechanism of action of active compounds. Correspondence

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Supercritical Carbon Dioxide Extraction of Essential Oils from Perovskia atriplicifolia Benth.

Cited by 56 publications

References 30 publications

Supercritical Fluid Extraction of Plant Flavors and Fragrances

Supercritical Fluid Extraction of Plant Flavors and Fragrances

Chemical Composition and Biological Activity of the Essential Oil ofPerovskia atriplicifolia. from Pakistan

Cytotoxicity of Marchantia convoluta leaf extracts to human liver and lung cancer cells

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