Supercritical fluid extraction of furanocoumarins from the fruits of <i>Archangelica off.</i> Hoffm

Gawdzik, J.; Kawka, S.; Mardarowicz, Marek; Suprynowicz, Z.; Wolski, T.

doi:10.1002/jhrc.1240181213

Cited by 6 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of extractions are presented in Table 2, and they compare the extraction yield of the furanocoumarins listed in Table 1. The levels of individual furanocoumarins are in accordance with previously reported results from exhaustive Soxhlet and supercritical fluid extractions (Gawdzik et al, 1996). It is clearly seen from Table 2 that the extraction yield with petroleum ether (40-60°C), and of methanol after petroleum ether, depended on the mode of extraction.…”

Section: Resultssupporting

confidence: 90%

Effect of extraction method on the yield of furanocoumarins from fruits of Archangelica ofﬁcinalis Hoffm.

Waksmundzka‐Hajnos

Petruczynik

Dragan

et al. 2004

Phytochemical Analysis

View full text Add to dashboard Cite

Optimal conditions for the extraction and analysis of furanocoumarins from fruits of Archangelica officinalis Hoffm. have been determined. The following extraction methods were used: exhaustive extraction in a Soxhlet apparatus, ultrasonication at 25 and 60 degrees C, microwave-assisted solvent extraction in open and closed systems, and accelerated solvent extraction (ASE). In most cases the yields of furanocoumarins were highest using the ASE method. The effects of extracting solvent, temperature and time of extraction using this method were investigated. The highest yield of furanocoumarins by ASE was obtained with methanol at 100-130 degrees C for 10 min. The extraction yields of furanocoumarins from plant material by ultrasonication at 60 degrees C and microwave-assisted solvent extraction in an open system were comparable to the extraction yields obtained in the time- and solvent-consuming exhaustive process involving the Soxhlet apparatus.

show abstract

Section: Resultssupporting

confidence: 90%

Effect of extraction method on the yield of furanocoumarins from fruits of Archangelica ofﬁcinalis Hoffm.

Waksmundzka‐Hajnos

Petruczynik

Dragan

et al. 2004

Phytochemical Analysis

View full text Add to dashboard Cite

show abstract

“…Thus, the yield of LFCs from a freeze dried matrix seemed to be controlled by the extraction temperature combined with a sufficient fluid density. The results of Gawdzik et al (1995Gawdzik et al ( , 1996, who used SFE to separate aroma components and LFCs from dried seeds of Archangelica officinalis Hoff., were similar to the present results obtained with freeze-dried samples. According to Gawdzik et al (1996), the highest yields were achieved at carbon dioxide density of 0.8 g/mL, but an increase in temperature at lower density (0.3 g/mL) led to an increase in the yield of 2 and 3 and other LFCs in the supercritical fluid extracts.…”

Section: Optimisation Of Extraction Pressure and Temperaturementioning

confidence: 99%

“…The extracts have been analysed by gas chromatography (GC) or high performance liquid chromatography (HPLC) depending upon the intention of the study, i.e. whether it is to analyse volatile aroma compounds (Vilegas et al, 1993;Kerrola and Kallio, 1994;Gawdzik et al, 1995) or just the furocoumarins and related metabolites (Chaudhary et al, 1985;Spencer et al, 1987;Baumann et al, 1988).…”

Section: Introductionmentioning

confidence: 99%

Quantitative determination of phototoxic furocoumarins in celeriac (Apium graveolens L. var. rapeceum) using supercritical fluid extraction and high performance liquid chromatography

1997

View full text Add to dashboard Cite

Linear phototoxic furocoumarins were determined in fresh celeriacs using supercritical fluid extraction (SFE) and reversed phase liquid chromatography. The SFE method was optimized by comparing extraction yields at different temperatures and pressures, resulting in the density of the carbon dioxide between 0.3 and 0.9 g/mL. The addition of a drying agent (sodium sulphate) to the sample was important in avoiding the plugging of the linear restrictor used. The optimum yields of furocoumarins were obtained when the density of the carbon dioxide was 0.58 g/mL. The repeatability was enhanced by careful selection of the collection solvent; however, between the solvents tested, only small differences in their efficiency to retain the analytes were observed. The determination of furocoumarins from fresh material was more efficient, and difficulties were observed in the isolation of the analytes from freeze‐dried or air‐dried ground celeriac. The amounts of furocoumarins varied within the batches of tubers, the sum of three phototoxic furocoumarins being 2.1–4.5 mg/kg (on a fresh weight basis). However, the yields obtained by SFE were in agreement with those from Soxhlet extraction. © 1997 John Wiley & Sons, Ltd.

show abstract

“…Coumarin content in Angelica archangelica [%] ingredient was imperatorine, which constituted from 1.31 to 2.57%. Further compounds are phellopterin (0.66%) and bergapten (0.33%) [78], bergapten (0.29%) and xanthotoxin (0.25%) [79] or bergapten (0.59%) and umbelliprenin (0.31%) [77] depending on the origin of the raw material. The imperatorine content was usually 2-4 times higher than the next compound.…”

Section: Fruitmentioning

confidence: 99%

“…The imperatorine content was usually 2-4 times higher than the next compound. Research shows that imperatorine can constitute even over 80% of the furanocoumarins fraction in angelica fruit [16,79].…”

Section: Fruitmentioning

confidence: 99%

Variability of composition of essential oil and coumarin compounds of Angelica archangelica L.

Forycka

Buchwald

2019

Herba Polonica

View full text Add to dashboard Cite

SummaryThe medicinal and culinary properties of Angelica archangelica L. have been known and valued since the Middle Ages. Ingredients of essential oil and coumarins found in this plant are to a large degree responsible for its pharmacological activity. This study is a review of the literature of the most important biologically active compounds present in herbal raw materials: root (rhizome with roots) and angelica fruits. Research shows that the content of individual compounds of the essential oil and coumarin fraction is variable, which may point to a large intraspecific variation. Therefore, these compounds may be good markers for identifying taxa or chemotypes in chemotaxonomic research valuable for the herbal medicine and pharmaceutical industry.

show abstract

Supercritical fluid extraction of furanocoumarins from the fruits of Archangelica off. Hoffm

Cited by 6 publications

References 7 publications

Effect of extraction method on the yield of furanocoumarins from fruits of Archangelica ofﬁcinalis Hoffm.

Effect of extraction method on the yield of furanocoumarins from fruits of Archangelica ofﬁcinalis Hoffm.

Quantitative determination of phototoxic furocoumarins in celeriac (Apium graveolens L. var. rapeceum) using supercritical fluid extraction and high performance liquid chromatography

Variability of composition of essential oil and coumarin compounds of Angelica archangelica L.

Contact Info

Product

Resources

About