Superfast Set, Strong and Less Degradable Mineral Trioxide Aggregate Cement

Abstract

Purpose Despite the good sealing ability and biocompatibility of mineral trioxide aggregate (MTA), its slow setting, high degradation, and weakness limit its use in surgical endodontics and high stress-bearing areas. This study aimed to develop two new liquids to control these drawbacks. They were prepared from calcium chloride, fumed silica, and hydroxyapatite or calcium phosphate and coded “H” and “P,” respectively. Methods Portland cement, Grey ProRoot® MTA, and white ProRoot MTA were mixed with distilled water (control) or liquid “H” or “P.” The pH, setting time, degradation rate, leachant/precipitate' composition, compressive strength, and morphology were assessed. Results Both liquids maintained MTA's high alkalinity and reduced the setting time by 1-2 orders of magnitude. Both liquids, H in particular, significantly reduced the degradation rate of Grey ProRoot and White ProRoot MTA®. Calcite has been identified as the main phase of the leachant or precipitate formed during the cement's degradation. Calcium hydroxide or hydroxyapatite was also identified with Grey ProRoot MTA mixed with H liquid. These liquids also significantly increased the compressive strength with no statistical differences between them; this was associated with the production of dense, consolidated structures. Conclusions The modified MTA could be used in surgical endodontics and high stress-bearing areas.

Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates

“…However, there are opposite findings about the biocompatibility of calcium silicate-based materials (MTA, Bioaggregate) which indicate that these materials adversely affect the liver and kidneys of the rat, causing significant inflammatory reactions in comparison to the control group [13,34,35]. Harmful effects are explained by the presence of small amounts of arsenic in the MTA material [12] which exceed the level recommended by the International Organization for Standardization [36][37][38][39]. is makes the present study, together with the previous biocompatibility studies of the new endodontic material ALBO-MPSA [14][15][16][17][18][19][20][21], very important as they give evidence about safety of the new material which would be used in the future in dental practice as an alternative to more toxic currently available materials.…”

“…However, MTA shows many drawbacks during the clinical application, such as long setting time, difficulty in handling, and potential discoloration of teeth [10][11][12], and therefore, researchers have been trying to introduce new materials which would overcome these limitations of MTA (Bioaggregate and Biodentine) [13].…”

Apicoectomy of Perforated Root Canal Using Bioceramic Cement and Photodynamic Therapy

“…MTA was indicated many years ago as an effective root-end filling material due to its biocompatibility and sealing ability [ 18 ], and since then, many bioceramic cements with the same intention presented similar results [ 22 , 34 ]. As well, modified MTA forms were indicated for high stress-bearing areas and especially for surgical sites [ 35 ].…”

Biocompatibility Study of a New Dental Cement Based on Hydroxyapatite and Calcium Silicates: Focus on Liver, Kidney, and Spleen Tissue Effects

“…The mineral trioxide aggregate (MTA) is certainly one of the most widely investigated calcium silicate-based materials due to its biocompatibility, bioactivity, and hard-tissue conductive and inductive properties [5][6][7][8][9]. Despite many good properties, MTA shows many drawbacks during clinical application, such as long setting time, difficult handling, and potential teeth discoloration [10][11][12]. Therefore, researchers in this field resulted in a synthesis of new materials that could overcome the limitations of MTA [13].…”

“…Despite many good properties, MTA shows many drawbacks during clinical application, such as long setting time, difficult handling, and potential teeth discoloration [ 10 , 11 , 12 ]. Therefore, researchers in this field resulted in a synthesis of new materials that could overcome the limitations of MTA [ 13 ].…”