Superficial Acral Fibromyxoma involving the nail's apparatus. Case report and literature review

García, A. Márquez; Mendonça, Francisco Manuel Ildefonso; Cejudo, Manuel Perea; Martínez, Francisco José Martínez; Ríos-Martín, Juan José

doi:10.1590/abd1806-4841.20142673

Cited by 8 publications

(9 citation statements)

References 8 publications

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“…SAFM is diagnosed with clinicopathological and immunohistochemical examination. It has a benign behavior; however, it may show persistance or recurrence if not treated properly . To date, 4 cases were reported with dermoscopic images in literature and our case is the fifth SAFM described with dermoscopic characteristics .…”

Section: Introductionmentioning

confidence: 75%

Superficial acral fibromyxoma in the heel with new vascular features on dermoscopy

Polat¹,

Karaali²,

Erdemir

et al. 2018

J Cutan Pathol

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Superficial acral fibromyxoma (SAFM) is an uncommon mesenchymal soft tissue tumor with a predilection for the acral extremites and nail bed involvement. SAFM is diagnosed with clinicopathological and immunohistochemical examination. Awareness of this rare tumor is important because of amounts of benign and malignant neoplasms. We report a case of SAFM in a rare localization in the heel with a new finding on dermoscopy.

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Section: Introductionmentioning

confidence: 75%

Superficial acral fibromyxoma in the heel with new vascular features on dermoscopy

Polat¹,

Karaali²,

Erdemir

et al. 2018

J Cutan Pathol

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“…Foram encontrados na literatura atual 314 casos descritos de FAS com localização variada, representados na tabela 1 . 1 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38…”

Section: Resultsunclassified

“…O tratamento desses tumores tipicamente envolve a excisão completa para excluir a malignidade e prevenir a recorrência, segundo dez trabalhos. 1 4 6 8 12 22 26 28 30 35…”

Section: Resultsunclassified

Fibromixoma acral superficial: Revisão da Literatura

et al. 2019

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Superficial acral fibromyxoma is a benign and rare tumor of the soft tissues. It usually manifests itself through a painless mass of slow growth that affects mainly males in the fifth decade of life. It usually affects the distal region, with a polypoid or dome-shaped appearance. The histological appearance is of a dermal mass without capsule, with spindle-shaped fibroblasts in a storiform or fasciculated pattern in the myxocollagenous stroma. The immunohistochemical evaluation of superficial acral fibromyxoma is usually positive for CD34 and CD99, with variable positivity for epithelial membrane antigen. The treatment consists of complete excision of the tumor mass.A review of the current literature on superficial acral fibromyxoma was performed, with an emphasis on the number of cases reported, location, diagnostic methods, histological characteristics, differential diagnoses and treatment.A total of 314 reported cases of superficial acral fibromyxoma with variable locations were found in the current literature, mainly in the toes (45.8%) and fingers (39.1%). It has a slightly superior incidence in men (61%) and enormous variability in the age range of occurrence.Superficial acral fibromyxoma is a single soft-tissue tumor that should enter the differential diagnosis of periungual and subungual acral lesions; the treatment consists of simple excision. More studies are needed to better understand this pathology, which was first described in 2001.

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“…Histologically, SAFM is composed of proliferation of fusiform fibroblasts inside a myxoid, myxocollagenous, or collagenous matrix. A rich microvascular network and local infiltration of mast cells can be seen in the tumor [1, 3, 10]. Immunohistochemistry is recommended for the diagnosis and shows CD34, CD99, and EMA positivity, while the results for neural and muscular markers (S-100, HMB-45, SMA, desmin, and actin) are negative [1, 10, 11].…”

Section: Discussionmentioning

confidence: 99%

“…It generally presents as a slow-growing painless nodule in middle-aged adults [1, 2]. SAFM has a benign behavior, but it may show persistence or recurrence if not properly treated [3]. Its differential diagnoses include other neoplasms, such as dermatofibrosarcoma protuberans and myxoid neurofibroma [2].…”

Section: Introductionmentioning

confidence: 99%

Superficial Acral Fibromyxoma, Appearing as Retronychia: A Rare Clinical Entity

Kalloniati¹,

Arampatzi²,

Christina³

et al. 2020

Skin Appendage Disord

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is a disorder caused by ingrowth of the proximal nail plate into the proximal nail fold and is suspected in cases of unresolved chronic proximal paronychia. • Superficial acral fibromyxoma is a rare benign tumor of soft tissues commonly located in the subungual or periungual area. Novel Insights • Total avulsion of the nail constitutes the treatment of choice for retronychia and can reveal the existence of a subungual superficial acral fibromyxoma as a cause of this condition.

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Superficial Acral Fibromyxoma involving the nail's apparatus. Case report and literature review

Cited by 8 publications

References 8 publications

Superficial acral fibromyxoma in the heel with new vascular features on dermoscopy

Superficial acral fibromyxoma in the heel with new vascular features on dermoscopy

Fibromixoma acral superficial: Revisão da Literatura

Superficial Acral Fibromyxoma, Appearing as Retronychia: A Rare Clinical Entity

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