“…As a renewable resource, natural wood not only has the advantages of extensive source and low cost but also has a highly ordered hierarchical structure, good mechanical properties, and biocompatibility. , Wood is composed of oriented cellulose nanofibers with unique mechanical anisotropy, which is similar to that of axially arranged collagen fibers in the periosteum . Moreover, after delignification treatment, the porous structure and oriented cellulose fiber skeleton of wood can be well maintained, which is expected to be used as an ideal and anisotropic high-strength fiber skeleton. , In recent years, wood has been widely used in energy storage, sensors, optical equipment, , and other fields. , However, the characteristics of wood, such as excellent biocompatibility, axially arranged porous structure, and anisotropic mechanical properties, have not been considered to guide the design of artificial periosteum. In addition, wood is a rigid material with poor flexibility and limited biofunctions in antibacterial, anti-inflammatory, and osteogenic activities .…”