We present an approach to power integrity analysis that is based on traces resulting from application execution. The first phase of the approach identifies a vector that maximally stresses the power grid, while the second phase entails simulation of the selected vector on an accurate grid model. We show, for an AV R32 32-bit microcontroller, that the vector we identify gives rise to a supply voltage drop that is 18% larger than that of the vector obtained in a regular flow, which considers average power dissipation per cycle.