Suppressing Aedes albopictus, an Emerging Vector of Dengue and Chikungunya Viruses, by a Novel Combination of a Monomolecular Film and an Insect-Growth Regulator

Nelder, Mark P.; Kesavaraju, Banugopan; Farajollahi, Ary; Healy, Sean P.; Ünlü, Işık; Crepeau, Taryn; Ragavendran, Ashok; Fonseca, Dina M.; Gaugler, Randy

doi:10.4269/ajtmh.2010.09-0546

Cited by 26 publications

(19 citation statements)

References 17 publications

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“…We chose Ae. albopictus for this study because of its rapid expansion in world-wide distribution and its emerging importance as a vector for Dengue and Chikungunya viruses [14]. Our analysis has doubled the number of known mosquito-specific miRNAs, uncovered miRNAs showing stage-specific and blood-meal-regulated expression profiles, and provided the basis for the investigations of the function and evolution of mosquito miRNAs.…”

Section: Introductionmentioning

confidence: 98%

miRNA Genes of an Invasive Vector Mosquito, Aedes albopictus

et al. 2013

PLoS ONE

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Aedes albopictus, a vector of Dengue and Chikungunya viruses, is a robust invasive species in both tropical and temperate environments. MicroRNAs (miRNAs) regulate gene expression and biological processes including embryonic development, innate immunity and infection. While a number of miRNAs have been discovered in some mosquitoes, no comprehensive effort has been made to characterize them from different developmental stages from a single species. Systematic analysis of miRNAs in Ae. albopictus will improve our understanding of its basic biology and inform novel strategies to prevent virus transmission. Between 10–14 million Illumina sequencing reads per sample were obtained from embryos, larvae, pupae, adult males, sugar-fed and blood-fed adult females. A total of 119 miRNA genes represented by 215 miRNA or miRNA star (miRNA*) sequences were identified, 15 of which are novel. Eleven, two, and two of the newly-discovered miRNA genes appear specific to Aedes, Culicinae, and Culicidae, respectively. A number of miRNAs accumulate predominantly in one or two developmental stages and the large number that showed differences in abundance following a blood meal likely are important in blood-induced mosquito biology. Gene Ontology (GO) analysis of the targets of all Ae. albopictus miRNAs provides a useful starting point for the study of their functions in mosquitoes. This study is the first systematic analysis of miRNAs based on deep-sequencing of small RNA samples of all developmental stages of a mosquito species. A number of miRNAs are related to specific physiological states, most notably, pre- and post-blood feeding. The distribution of lineage-specific miRNAs is consistent with mosquito phylogeny and the presence of a number of Aedes-specific miRNAs likely reflects the divergence between the Aedes and Culex genera.

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Section: Introductionmentioning

confidence: 98%

miRNA Genes of an Invasive Vector Mosquito, Aedes albopictus

et al. 2013

PLoS ONE

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“…Additionally, indoor living space can be sprayed with pyrethrin to control populations that inhabit human living spaces (Monath & Cetron, 2002 (Tantely et al, 2010). Monomolecular films can also be applied to larval habitats which stop larvae and pupae from staying at the surface of the water (Nelder et al, 2010).…”

Section: Source Reductionmentioning

confidence: 99%

A Review of the Invasive Mosquitoes in Europe: Ecology, Public Health Risks, and Control Options

Medlock¹,

Hansford²,

Schaffner

et al. 2012

Vector-Borne and Zoonotic Diseases

576

511

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There has been growing interest in Europe in recent years in the establishment and spread of invasive mosquitoes, notably the incursion of Aedes albopictus through the international trade in used tires and lucky bamboo, with onward spread within Europe through ground transport. More recently, five other non-European aedine mosquito species have been found in Europe, and in some cases populations have established locally and are spreading. Concerns have been raised about the involvement of these mosquito species in transmission cycles of pathogens of public health importance, and these concerns were borne out following the outbreak of chikungunya fever in Italy in 2007, and subsequent autochthonous cases of dengue fever in France and Croatia in 2010. This article reviews current understanding of all exotic (five introduced invasive and one intercepted) aedine species in Europe, highlighting the known import pathways, biotic and abiotic constraints for establishment, control strategies, and public health significance, and encourages Europe-wide surveillance for invasive mosquitoes.

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“…2013, 98 fewer cases compared to year 2012 (Ministry of Health Malaysia, 2013). In addition to Aedes aegypti, A. albopictus is an important vector of dengue virus (Nelder et al, 2010). This mosquito is native to Asia and is also known as the Asian tiger mosquito (Usmani-Brown et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Population genetic structure of Aedes albopictus in Penang, Malaysia

Zawani¹,

Abu²,

Sazaly³

et al. 2014

Genet. Mol. Res.

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ABSTRACT. The mosquito Aedes albopictus is indigenous to SoutheastAsian and is a vector for arbovirus diseases. Studies examining the population genetics structure of A. albopictus have been conducted worldwide; however, there are no documented reports on the population genetic structure of A. albopictus in Malaysia, particularly in Penang. We examined the population genetics of A. albopictus based on a 445-base pair segment of the mitochondrial DNA cytochrome oxidase 1 gene among 77 individuals from 9 localities representing 4 regions (Seberang Perai Utara, Seberang Perai Tengah, Northeast, and Southwest) of Penang. A total of 37 haplotypes were detected, including 28 unique haplotypes. The other 9 haplotypes were shared among various populations. These shared haplotypes reflect the weak population genetic structure of A. albopictus. The phylogenetic tree showed a low bootstrap value with no genetic structure, which was supported by minimum spanning network analysis. Analysis of mismatch distribution showed poor fit of equilibrium distribution. The genetic distance showed low genetic variation, while pairwise F ST values showed no significant difference between all regions in Penang except for some localities. High haplotype diversity and low nucleotide diversity was observed for cytochrome oxidase 1 mtDNA. We conclude that there is no population genetic structure of A. albopictus mosquitoes in the Penang area.

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Suppressing Aedes albopictus, an Emerging Vector of Dengue and Chikungunya Viruses, by a Novel Combination of a Monomolecular Film and an Insect-Growth Regulator

Cited by 26 publications

References 17 publications

miRNA Genes of an Invasive Vector Mosquito, Aedes albopictus

miRNA Genes of an Invasive Vector Mosquito, Aedes albopictus

A Review of the Invasive Mosquitoes in Europe: Ecology, Public Health Risks, and Control Options

Population genetic structure of Aedes albopictus in Penang, Malaysia

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