Suppression of synthesis of serotonin: Effect on antinociception induced by microwave irradiation and analgesic remedies

Nesin, E. N.

doi:10.1007/s11062-006-0082-2

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…Ïðîòå â³äîìî, ùî íèçüêî³í-òåíñèâí³ åëåêòðîìàãí³òí³ ïîëÿ îïòè÷íîãî òà ì³êðîõâèëüîâîãî ä³àïàçîíó ñóòòºâî ïîòåí-ö³þþòü àíàëüãåòè÷íó ä³þ îï³î¿äíèõ ³ íåî-ï³î¿äíèõ àíàëüãåòèê³â [6,8]. Î÷åâèäíî, ôàðìàêîëîã³÷í³ àíàëüãåòèêè ³ âèñîêî÷àñ-òîòí³ íèçüêî³íòåíñèâí³ åëåêòðîìàãí³òí³ ïîëÿ âèÿâëÿþòü ñõîaeó ä³þ íà áîëüîâ³ ïîâåä³í-êîâ³ ðåàêö³¿ ó ãðèçóí³â, âèêîðèñòîâóþ÷è îäí³ é ò³ ñàì³ àíòèíîöèöåïòèâí³ ñèñòåìè ñòîâáóðà ìîçêó [7,12,21]. Ìè ââàaeàºìî, ùî ï³äñèëåííÿ àíàëüãåòè÷íîãî åôåêòó êîðâ³òèíó, êîëè â³í çàñòîñîâóºòüñÿ â êîìá³íàö³¿ ç íèçüêî³íòåíñèâíèì ÏÑ, òàêîae ìîaeå áóòè çóìîâëåíî àêòèâàö³ºþ îäíèõ ³ òèõ ñàìèõ àíòèíîöèöåïòèâíèõ ñèñòåì ñòîâáóðà ìîçêó.…”

Section: ðåçóëüòàòè òà ¯õ îáãîâîðåííßunclassified

Action of red polarized light on the acupuncture point E-36 increases analgesic effect of corvitin

Za¹,

IuP²,

Oi³

et al. 2010

Fiziol Zh

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Ä³ÿ ÷åðâîíîãî ïîëÿðèçîâàíîãî ñâ³òëà íà òî÷êó àêóïóíêòóðè Å-36 ï³äñèëþº ïðîòèáîëüîâèé åôåêò êîðâ³òèíó Íà ìîäåë³ ôîðìàë³íîâîãî òåñòó äîñë³äaeóâàëè ìîaeëèâ³ñòü ïîñèëåííÿ ïðîòèáîëüîâîãî åôåêòó êîðâ³òèíó ó ìèøåé ë³í³é Ñ57ÂL/6J ³ ÑBA/CaLac ä³ºþ ÷åðâîíîãî ïîëÿðèçîâàíîãî ñâ³òëà (ÏÑ) íà òî÷êó àêóïóíêòóðè (ÒÀ) Å-36. Ðåºñòðóâàëè òðèâàë³ñòü áîëüîâî¿ ïîâåä³íêîâî¿ ðåàêö³¿ (âèëèçóâàííÿ óðàaeåíî¿ ê³íö³âêè), âèêëèêàíî¿ ³íºêö³ºþ 5%-ãî ðîç÷èíó ôîðìàë³íó â ñòîïó (0,25 ìêë, ï³äøê³ðíî) äî òà ï³ñëÿ ñèñòåìíîãî ââåäåííÿ êîðâ³òèíó (10 ìã/êã, âíóòð³øíüî÷åðåâèííî) àáî ñóêóïíîãî çàñòîñóâàííÿ êîðâ³òèíó ³ ÷åðâîíîãî ÏÑ (10-õâèëèííèé ñåàíñ â³äðàçó ï³ñëÿ ñòâîðåííÿ îñåðåäêó áîëþ). Óñòàíîâëåíî, ùî ï³ñëÿ àïë³êàö³¿ ÏÑ íà ïðîòèáîëüîâó ÒÀ Å-36 ó âñ³õ òâàðèí äîñòîâ³ðíî ï³äñèëþºòüñÿ ïðîòèáîëüîâèé åôåêò êîðâ³òèíó. Ó ìèøåé ë³í³¿ Ñ57ÂL/6J çàñòîñóâàííÿ îäíîãî êîðâ³ò³íó ïîñëàáëþâàëî áîëüîâó ðåàêö³þ íà 29,7 %, à ïðè ñóêóïíîìó âèêîðèñòàíí³ ÷åðâîíîãî ÏÑ ³ êîðâ³òèíó íà 53,1 %. Ìèø³ ë³í³¿ ÑBA/CaLac áóëè ìåíø ÷óòëèâ³ ÿê äî êîðâ³òèíó, òàê ³ äî ÏÑ. Êîðâ³òèí âèêëèêàâ ó íèõ ñêîðî÷åííÿ òðèâàëîñò³ áîëüîâî¿ ðåàêö³¿ íà 14 %, à ïðè ñïîëó÷åíí³ ç ÷åðâîíèì ÏÑ íà 32,4 %. Íåòðàâìàòè÷íèé, áåç ïîá³÷íèõ åôåêò³â ìåòîä ä³¿ íèçüêî³íòåíñèâíèì ÏÑ ìîaeå áóòè ðåêîìåíäîâàíèé õâîðèì, ÿê³ ïðèéìàþòü êîðâ³òèí, äëÿ ïîñèëåííÿ éîãî åôåêòèâíîñò³. Êëþ÷îâ³ ñëîâà: êîðâ³òèí, ïîëÿðèçîâàíå ñâ³òëî, ôîðìàë³íîâèé òåñò, àíàëüãåç³ÿ, òî÷êà àêóïóíêòóðè Å-36.

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Section: ðåçóëüòàòè òà ¯õ îáãîâîðåííßunclassified