Supra-vesical Urinary Diversion and Ureteric Re-implantation for Malignant Disease

Woodhouse, Christopher

doi:10.1016/j.clon.2010.07.005

Cited by 17 publications

(6 citation statements)

References 22 publications

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“…The structure and function of the ureter can be restored by means of transureteroureterostomy only when ureteral lesions and defects are small and associated damages are limited [19]. In case of extensive ureteral injuries, complex surgical procedures are usually required.…”

Section: Discussionmentioning

confidence: 99%

Seeding Homologous Adipose-Derived Stem Cells and Bladder Smooth Muscle Cells Into Bladder Submucosa Matrix for Reconstructing the Ureter in a Rabbit Model

Meng

Liao

Yang

et al. 2015

Transplantation Proceedings

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Section: Discussionmentioning

confidence: 99%

Seeding Homologous Adipose-Derived Stem Cells and Bladder Smooth Muscle Cells Into Bladder Submucosa Matrix for Reconstructing the Ureter in a Rabbit Model

Meng

Liao

Yang

et al. 2015

Transplantation Proceedings

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“…c A firm sheet of connective tissue around the stent can be seen at the end of 3 weeks with fibroblastic proliferation, the inflammatory response was entirely absent. Inset scale bar 300 lm Transuretero-ureterostomy is a feasible solution only for short ureteral defect or stricture [26,27]. However, reconstruction of extensive ureteral injuries remains a real challenge to urologists.…”

Section: Discussionmentioning

confidence: 99%

Autologous urothelial cells transplantation onto a prefabricated capsular stent for tissue engineered ureteral reconstruction

Xu¹,

Fu²,

Li³

et al. 2012

J Mater Sci: Mater Med

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In this study, we have fabricated an artificial ureter by transplantation of in vitro-expanded urothelial cells onto an in vivo-prefabricated capsular stent using tissue engineering methods. Spiral poly (L-lactic acid) (PLLA) stents were transplanted into the subcutaneous of Wistar rats for a period of 1, 2 or 3 weeks to induce the formation of connective tissue capsules on their surfaces. The capsular PLLA stents were then decellularized and further recellularized with bladder epithelial cells to fabricate artificial ureters. The results showed that the entrapped cells in all capsules remained continuously proliferation and lined up in continuous layers. In addition, the urothelial cells on the capsular stents with an embedding period of 2 or 3 weeks showed higher proliferative viability compared with the cells on the stents with an embedding time of 1 week (P < 0.05). The results of the study indicated that the prefabricated capsular stents could serve as alternative cell carriers for tissue engineered ureters, especially with embedding time from 2 to 3 weeks.

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“…The combination of these conditions with ureteric obstruction due to retroperitoneal, ureter compressing masses oftentimes leads to the insertion of ureteral stents. Regardless, less than 50% of patients with malignant ureteric obstruction survive less than 6 months after the insertion of initial stent [15] . Open surgery to relieve the obstruction should be limited to those patients with a life expectancy of more than 6 months.…”

Section: Discussionmentioning

confidence: 99%

“…However, in many situations, one problem may just be replaced by another at the expense of painful surgery close to the end of life. Therefore, in many cases, an open surgical supravesical diversion is the last thing to be considered, not the first [15] . Open approaches normally require major surgery, and their feasibility is based on the willingness of the individual, a reasonable level of fitness and expected length of life in the patient.…”

Section: Discussionmentioning

confidence: 99%

Transvesical Suprapubic Externalization of Ureteral Stents - Introduction of a Surgical Innovation at the Development Stage

Gerullis

Schwartmann²,

Ecke³

et al. 2017

Urol Int

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Background and Objectives: In this study, we describe our first experiences with the new method of transvesical suprapubic externalization of ureteral stents. This method is assessed in patients with incurable ureteral obstruction and concomitant bladder dysfunction, and is classified according to the Idea, Development, Exploration, Assessment, Long-Term Study (IDEAL) recommendations. Patients and Methods: From 2009 to 2015, transvesical suprapubic externalization of ureteral stents was applied in 14 (8 males, 6 females) patients with incurable ureteral obstruction of malignant (n = 9, 64%) or benign (n = 5; 36%) etiology. All the patients had concomitant bladder pathologies that impaired quality of life (QoL). Classification according to IDEAL followed the respective recommendations. Results: Only minor complications, except 1 major complication not directly related to the procedure, were observed. QoL improvement was reported in all patients. The duration for this surgery was 45 (17-86) min; however, it varied between genders (female 37 min, male 51 min). The mean follow-up period was 26.6 months ranging from 12 to 73 months. Transvesical suprapubic externalization of ureteral stents resulted in a stable renal function and the elimination of urinary leakage via a compromised bladder in all patients. Conclusions: Transvesical externalization of ureteral stents is a feasible method for urinary diversion, which seems to improve patients' QoL in appropriate indications. The method can be classified as IDEAL stage 2a.

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Supra-vesical Urinary Diversion and Ureteric Re-implantation for Malignant Disease

Cited by 17 publications

References 22 publications

Seeding Homologous Adipose-Derived Stem Cells and Bladder Smooth Muscle Cells Into Bladder Submucosa Matrix for Reconstructing the Ureter in a Rabbit Model

Seeding Homologous Adipose-Derived Stem Cells and Bladder Smooth Muscle Cells Into Bladder Submucosa Matrix for Reconstructing the Ureter in a Rabbit Model

Autologous urothelial cells transplantation onto a prefabricated capsular stent for tissue engineered ureteral reconstruction

Transvesical Suprapubic Externalization of Ureteral Stents - Introduction of a Surgical Innovation at the Development Stage

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