Sur les relations croisées des caractères antigènes et immunigènes des virus de la maladie de Carré et de la peste bovine : état actuel des recherches

Abstract

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Canine Distemper Virus

“…Rabbits were not protected by virulent or avianized CDV against lapinized RV, even when large doses, repeated inoculations and adjuvants were employed MORNET et al, 1960;PLOWRIGHT, 1962).…”

“…Passive immunization of dogs (POLDING et al, 1959) or ferrets with hyperimmune RV antiserum was unsuccessful, although in vitro neutralization was found by some authors MORNET et al, 1960;IMAGAWA et al, 1960) but not by others DELAY et al, 1965) using different test systems. In agar gel diffusion tests, spur formation was seen when hyperimmune RV antiserum prepared in rabbits was diffused against CDV and RV antigens, indicating a difference in antigens (WHITE et al, 1961).…”

“…In vitro neutralization of RV by CDV antiserum was found to a limited degree (POLDING and SIMPSON, 1957;MORNET et al, 1960;VILLEMONT et al, 1961;DELAY et al, 1965). In agar gel diffusion tests, fusing lines were seen when hyperimmune CDV antiserum prepared in dogs diffused against RV and CDV antigens indicating identity (WHITE et al, 1961).…”