Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices

Franke, Thomas; Abate, Adam R.; Weitz, David A.; Wixforth, Achim

doi:10.1039/b906819h

Cited by 314 publications

(251 citation statements)

References 17 publications

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“…Many applications require control over position and concentration of the objects in order to induce mixing, 3 chemical reactions, 4 biomolecular tagging, 5 or a host of other processes. The necessary manipulations of the objects often rely on actively applying various external force fields, including hydrodynamic (inertial), [6][7][8] electrokinetic, 9-12 dielectrophoretic, [13][14][15][16] magnetic, 17,18 optical 19,20 or acoustic [21][22][23] (ultrasound standing waves, surface acoustic waves) forces. Such forces will usually act differently on particles depending on their size, geometry, and mechanical or electromagnetic properties; as a result, particle separation and sorting become possible.…”

Section: Introductionmentioning

confidence: 99%

Efficient manipulation of microparticles in bubble streaming flows

Wang

Jalikop

Hilgenfeldt³

2012

Biomicrofluidics

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Oscillating microbubbles of radius 20-100 lm driven by ultrasound initiate a steady streaming flow around the bubbles. In such flows, microparticles of even smaller sizes (radius 1-5 lm) exhibit size-dependent behaviors: particles of different sizes follow different characteristic trajectories despite density-matching. Adjusting the relative strengths of the streaming flow and a superimposed Poiseuille flow allows for a simple tuning of particle behavior, separating the trajectories of particles with a size resolution on the order of 1 lm. Selective trapping, accumulation, and release of particles can be achieved. We show here how to design bubble microfluidic devices that use these concepts to filter, enrich, and preconcentrate particles of selected sizes, either by concentrating them in discrete clusters (localized both stream-and spanwise) or by forcing them into narrow, continuous trajectory bundles of strong spanwise localization.

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Section: Introductionmentioning

confidence: 99%

Efficient manipulation of microparticles in bubble streaming flows

Wang

Jalikop

Hilgenfeldt³

2012

Biomicrofluidics

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“…Surface acoustic wave is another useful method that can direct the motion of droplets in microfluidic channels and be used for droplet sorting [58]. The surface acoustic wave device is assembled on top of the surface of a piezoelectric substrate, on which an interdigital transducer of gold electrodes is fabricated.…”

Section: Droplet Sortingmentioning

confidence: 99%

Basic Technologies for Droplet Microfluidics

Zeng

Liu

Xie

et al. 2011

Topics in Current Chemistry

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In recent years droplet microfluidics has become a quickly evolving research field. The availability of a wide range of technologies for droplet generation and manipulation has enabled the applications of droplet microfluidics in a wide variety of fields, from single cell analysis to material synthesis. In this review we summarize the main technologies for droplet microfluidics and discuss the recent advances in technologies that enable droplets as microreactors with complete functions. Applications of microdroplets in chemical reactions, particle synthesis, and single cell analysis are also briefly reviewed.

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“…Manipulation of droplets in a precise and flexible manner plays a vital role in these applications. A number of approaches have been commonly used to manipulate the dynamical behavior of droplets in microfluidics, including electrowetting on dielectric (EWOD) [1,2], dielectrophoresis (DEP) [3,4], hydrodynamic stress [5,6,7], thermocapillary force [8,9,10,11], surface acoustic wave [12], magnetic force [13,14], and optical forces [15,16]. In recent years, a novel use of surface energy gradients was demonstrated to guide or anchor droplets against a mean flow in a confined microchannel [17,18].…”

Section: Introductionmentioning

confidence: 99%

Lattice Boltzmann simulation of the trapping of a microdroplet in a well of surface energy

Liu

Zhang

2017

Computers & Fluids

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This version is available at https://strathprints.strath.ac.uk/58315/ Strathprints is designed to allow users to access the research output of the University of Strathclyde. Unless otherwise explicitly stated on the manuscript, Copyright © and Moral Rights for the papers on this site are retained by the individual authors and/or other copyright owners. Please check the manuscript for details of any other licences that may have been applied. You may not engage in further distribution of the material for any profitmaking activities or any commercial gain. You may freely distribute both the url (https://strathprints.strath.ac.uk/) and the content of this paper for research or private study, educational, or not-for-profit purposes without prior permission or charge.Any correspondence concerning this service should be sent to the Strathprints administrator: strathprints@strath.ac.ukThe Strathprints institutional repository (https://strathprints.strath.ac.uk) is a digital archive of University of Strathclyde research outputs. It has been developed to disseminate open access research outputs, expose data about those outputs, and enable the management and persistent access to Strathclyde's intellectual output. Lattice Boltzmann Simulation of the Trapping of a Microdroplet in a Well of Surface EnergyHaihu Liu a, * ,Y o n g h a oZ h a n g b AbstractIn this paper, a three-dimensional phase-field lattice Boltzmann method is used to simulate the dynamical behavior of a droplet, subject to an outer viscous flow, in a microchannel that contains a cylindrical hole etched into its top surface.The influence of the capillary number and the hole diameter (expressed as the ratio of hole diameter to channel height, b) is investigated. We demonstrate numerically that the surface energy gradient induced by the hole canc r e a t ea n anchoring force to resist the hydrodynamic drag from the outer flow, resulting in the droplet anchored to the hole when the capillary number is below a critical value. As b increases, the droplet can be anchored more easily. For b<2, the droplet partially enters into the hole and forms a spherical cap; whereas for b>2, the spherical cap of droplet reaches the top wall of the hole, making the hole depth into an additional important parameter. These observations are consistent with the previously reported experiments. However, the droplet does

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Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices

Abstract: We direct the motion of droplets in microfluidic channels using a surface acoustic wave device. This method allows individual drops to be directed along separate microchannel paths at high volume flow rates, which is useful for droplet sorting.

Cited by 314 publications

References 17 publications

Efficient manipulation of microparticles in bubble streaming flows

Efficient manipulation of microparticles in bubble streaming flows

Basic Technologies for Droplet Microfluidics

Lattice Boltzmann simulation of the trapping of a microdroplet in a well of surface energy

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