Surface calcification of hydrophilic acrylic intraocular lens related to inflammatory membrane formation after combined vitrectomy and cataract surgery

Lee, Sung‐Jin; Choi, Joon Ho; Sun, Hae Jung; Choi, Kyung Seek; Jung, Gi Yong

doi:10.1016/j.jcrs.2009.08.045

Cited by 40 publications

(34 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Even though migration of gas or silicone oil into the anterior chamber through the zonular fibers is possible, their presence in the anterior chamber was not necessarily observed in the cases we received or the cases described in the literature. 20,28,29 This current study also clearly demonstrates that the distinctive pattern of localized calcification is not associated with a particular IOL design or manufacturer. In summary, the cases described in our study as well as in others warrant consideration to avoid use of hydrophilic acrylic IOLs when procedures using intracameral air or gas, particularly DSEK or DSAEK, are anticipated.…”

Section: Discussionsupporting

confidence: 55%

“…A,B Vitreous tamponade with gas or silicone oil has also led to localized anterior surface calcification, as in 1 of the cases described by Dhital et al 20 and in 2 cases each after combined vitrectomy and cataract surgery described by Lee et al 28 and Walker et al 29 Migration of gas or silicone oil into the anterior chamber via zonular fiber defects remains a possibility after vitreous tamponade, as the pattern of calcification in all these cases suggests a change initially localized to the area of the IOL surface in direct contact with the anterior chamber contents.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Localized opacification of hydrophilic acrylic intraocular lenses after procedures using intracameral injection of air or gas

Werner¹,

Wilbanks²,

Nieuwendaal³

et al. 2015

Journal of Cataract and Refractive Surgery

102

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 55%

Section: Discussionmentioning

confidence: 99%

Localized opacification of hydrophilic acrylic intraocular lenses after procedures using intracameral injection of air or gas

Werner¹,

Wilbanks²,

Nieuwendaal³

et al. 2015

Journal of Cataract and Refractive Surgery

102

View full text Add to dashboard Cite

show abstract

“…A,B Vitreous tamponade with gas or silicone oil has also led to localized anterior surface calcification, as in 1 case of Dithal et al 2 and in 2 cases after combined vitrectomy and cataract surgery described by Lee et al, 3 as well as other cases analyzed by one of us ( Figure 2). Migration of gas or silicone oil to the anterior chamber via zonular defects remains a possibility after vitreous tamponade, as the pattern of calcification in all these cases appears to suggest a change initially localized to the area of the IOL surface in direct contact with the anterior chamber contents.…”

mentioning

confidence: 78%

Localized calcification of hydrophilic acrylic intraocular lenses in association with intracameral injection of gas

Werner¹,

Wilbanks²,

Ollerton³

et al. 2012

Journal of Cataract and Refractive Surgery

View full text Add to dashboard Cite

We would like to call attention to a phenomenon of calcification of various hydrophilic acrylic intraocular lenses (IOLs) following procedures using intracameral injections of gas. Calcification is localized to the anterior surface/subsurface of the IOL and within the pupillary area. Poor quality of vision through the opacification has required IOL exchange in several cases. The explanted IOLs were analyzed by us and others.Saeed et al. 1 described a case in which sulphur hexafluoride and later perfluoropropane gas was used intracamerally to manage large iatrogenic Descemet membrane detachments observed during cataract surgery. A few weeks later, a fine haze was observed under the anterior surface of the hydrophilic acrylic IOL. Details on the aspect or nature of the IOL opacification were, however, not available in the report. Three cases of calcification of hydrophilic acrylic IOLs associated with intraocular injection of gas were recently compiled by Dhital et al. 2 The explanted IOL from one of those cases was analyzed in our laboratory. The patient, who had a history of Fuchs endothelial corneal dystrophy, had phacoemulsification with implantation of a hydrophilic acrylic IOL combined with Descemet-stripping automated endothelial keratoplasty (DSAEK) in February 2007, with subsequent intracameral injections of air and gas. The DSAEK was repeated in August 2007 with a complete gas fill of the anterior chamber. Approximately 1 month later, a central circular area of IOL opacification was noted. In the other 2 cases, IOL opacification was observed after intracameral injection of gas to control hypotony following trabeculectomy and after vitrectomy with cryotherapy and intravitreous injection of gas in an eye with a history of blunt trauma, respectively. The 3 cases by Dhital et al. 2 shared a distinctive pattern of opacification limited to the anterior surface and/or subsurface of the IOL and defined by the pupillary margin. The calcific nature of the deposits observed within the area of opacification was confirmed by histochemical staining and scanning electron microscopy coupled with energy-dispersive x-ray spectroscopy. 2 Our laboratory has recently analyzed another similar case of localized IOL calcification following DSAEK. The patient had Fuchs dystrophy and had had uneventful phacoemulsification with hydrophilic acrylic IOL implantation in June 2010. Descemetstripping automated endothelial keratoplasty with intracameral injections of air was performed in October 2010. Two months later, the patient complained of "foggy" vision. Opacification of the anterior surface of the IOL within the pupillary area was observed. Figure 1. Case of localized hydrophilic acrylic IOL opacification after DSAEK, leading to explantation. A: Clinical photograph taken after pupil dilation. The arrows delineate the area of opacification, which is denser in the upper right quadrant. B: Gross photograph of the IOL, which was bisected for explantation. C: Light photomicrograph of the explanted IOL showing the presence of deposits o...

show abstract

“…9 That is why long-term observation is necessary after implantation of hydrophilic acrylic IOLs, especially in cases in which bloodaqueous barrier breakdown is suspected, as may occur in diabetes, uveitis and vitrectomy. 19,20 The IOL opacification/discoloration has also been associated with the long-term use of systemic medications. Amiodarona and rifabutin had already been reported in patients with opacified lenses.…”

Section: B Discussionmentioning

confidence: 99%

Case-control study for clinical findings on intraocular lens opacity

Jorge¹,

Jorge²,

Ventura³

et al. 2014

Medical Express

View full text Add to dashboard Cite

OBJECTIVE: To evaluate clinical features of patients related to opacification of hydrophilic acrylic intraocular lenses, four years after surgery. METHODS: We evaluated six cases of late opacification of Ioflex intraocular lenses (case group) compared to 24 patients (control group) with no opacification. Both groups underwent phacoemulsification as a result of a community campaign for underprivileged people. Patients who underwent bilateral cataract surgery had only the right eye included on the study. The patients were submitted to ophthalmic examination, including measurements of corrected distance visual acuity and biomicroscopy slitlamp evaluation. Detailed medical histories were obtained. Surgical details were retrieved. RESULTS: Systemic arterial hypertension was recorded in 4 patients from the case group and 11 in the control group, with no statistically significant difference between groups. A single patient in the control group had diabetes mellitus, and so was not considered for statistical analysis. No environmental factor could be related. There were no statistically significant differences for mean visual acuity between the groups of patients regarding the evaluation periods. One eye in the control group received an Ioflex intraocular lens with the same lot number as one of the opacified lenses. CONCLUSION: No clear patient factor could be related to late Ioflex lens opacification.

show abstract

Surface calcification of hydrophilic acrylic intraocular lens related to inflammatory membrane formation after combined vitrectomy and cataract surgery

Abstract: No author has a financial or proprietary interest in any material or method mentioned.

Cited by 40 publications

References 18 publications

Localized opacification of hydrophilic acrylic intraocular lenses after procedures using intracameral injection of air or gas

Localized opacification of hydrophilic acrylic intraocular lenses after procedures using intracameral injection of air or gas

Localized calcification of hydrophilic acrylic intraocular lenses in association with intracameral injection of gas

Case-control study for clinical findings on intraocular lens opacity

Contact Info

Product

Resources

About