Surface characterization of biopolyurethanes based on cellulose derivatives

Abstract

Surface tension parameters and surface morphology of biopolyurethanes based on cellulose derivatives thin films, before and after HF cold plasma treatment has been investigated. Calculations are based on the geometric mean approach of Owens and Wendt, Rabel and Kälble, on the Lifshitz-van der Waals acid/base approach of van Oss and co-workers and on the theoretical methods involving quantitative structure-property relationship. For all the investigated samples the polar component contributes significantly to the total surface tensions, as due to the large electron donor interactions. HF cold plasma treatment modifies the surface energy of biopolyurethanes by changing their surface polarity and hydrophilicity. The hydrophilic/hydrophobic balance was studied by means of the free energy of hydration between the biomaterial film and water. The protein adsorption tests of fibrinogen were effected to evaluate the applicability of these biopolyurethanes as biomedical thromboresistant devices.

Tailorable polyelectrolyte protein complex based on poly(aspartic acid) and bovine serum albumin

“…[16] The total SFE and the components were calculated using the acid/base (LW/AB) approach of van oss and good (Equation (3)) [17] which divides the total SFE into dispersive Lifshitz-van der Waals interaction ( (Table 1). [18][19][20] Subscripts 'lv' and 'sv' denote the interfacial liquid-vapor and surface-vapor tensions, respectively, TOT sv . Blood compatibility is dictated by the manner in which their surfaces interact with blood constituents, like red blood cells and platelets.…”

Natural-Based Polyurethane Biomaterials for Medical Applications

“…Among the PPG-HPC, PTHF-HPC and PEA-HPC samples the most promising thromboresistant ones are PTHF-HPC and PEA-HPC. In our previous paper, the fibrinogen adsorption tests, (Macocinschi et al, 2009a), revealed that PTHF-HPC and PEA-HPC polyurethanes proved to be indicated for thromboresistant devices, and the polyether-urethane PTHF-HPC proved to have more relevant haemocompatible material qualities. From literature for Biospan polyurethane, (Korematsu et al, 1999), the values for adhered thrombocytes found are 101500 adhered thrombocytes per mm 2 .…”

“…Polyester-and polyether-urethanes have been modified with hydroxypropyl cellulose aiming the change of their surface and bulk characteristics to confer them biomaterial qualities Macocinschi et al, 2009a;Macocinschi et al, 2009b). In this respect, dynamic contact angle measurements, dynamic mechanical analyses accompanied by mechanical testing have been done.…”

Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices

“…Polyester-and polyether-urethanes have been modified [11][12][13], with hydroxypropyl cellulose to improve their surface characteristics and to generate biomaterial qualities. Platelet adhesion test has been carried out in vitro and it was found that the cellulose component in the polyurethane matrix reduces the platelet adhesion.…”

“…For estimation of the haemocompatibility properties of the obtained materials, water sorption was determined as well as the amount of fibrinogen adsorbed from solution, the amount of fibrinogen adsorbed from blood plasma, and the time of prothrombin consumption [12].…”