Surface characterization of polysulfone membranes modified by DNA immobilization

Zhao, Changsheng; Liu, Xiangdong; Rikimaru, Satoshi; Nomizu, Motoyoshi; Nishi, Norio

doi:10.1016/s0376-7388(02)00524-0

Cited by 65 publications

(39 citation statements)

References 28 publications

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“…This explains why the value of the octanol-water distribution coefficient had such an important effect on the removal ratio (Zhao et al 2004c). In addition, it has been reported that double-stranded DNA has a bias towards the selective removal and accumulation of endocrine disruptors with a planar structure (Yamada et al 2002).…”

Section: Accumulation and Removal Of Endocrine Disruptorsmentioning

confidence: 97%

“…Thus, on encapsulating the double-stranded DNA in hollow PSf microspheres using a liquid-liquid phase-separation technique, the resulting modified microspheres were capable of removing ethidium bromide -a DNA-intercalating material (Zhao et al 2004a). Such DNA-loaded PSf microspheres have a potential use in environmental applications and in gene delivery (Zhao et al 2004b).…”

Section: Introductionmentioning

confidence: 99%

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DNA-Modified Polysulphone Microspheres for Endocrine Disruptors and Heavy Metal Ions Removal

Zhao

Shi

Xie

et al. 2005

Adsorption Science & Technology

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Porous polysulphone (PSf) microspheres were modified by blending DNA into them and immobilizing DNA onto their surfaces. The DNAmodified microspheres, which were stable in water, were then used to remove endocrine disruptors and heavy metal ions from their aqueous solutions. Such microspheres could effectively accumulate pollutant compounds and endocrine disruptors, such as ethidium bromide, Acridine Orange, biphenyl, dibenzofuran and dibenzo-p-dioxin from their aqueous solutions. PSf microspheres without DNA also accumulated and removed endocrine disruptors due to their porosity and the hydrophobic interaction between the endocrine disruptors and PSf. Endocrine disruptors with and without a planar structure were effectively accumulated and removed by the DNA-modified PSf microspheres. In addition, PSf microspheres were found to be capable of selectively removing heavy metal ions such as Zn , Cd 2+ and Ag + from their aqueous solutions. These results show that DNA can be used to modify PSf microspheres, with the DNAmodified microspheres having a potential use in environmental applications.

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Section: Accumulation and Removal Of Endocrine Disruptorsmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

DNA-Modified Polysulphone Microspheres for Endocrine Disruptors and Heavy Metal Ions Removal

Zhao

Shi

Xie

et al. 2005

Adsorption Science & Technology

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“…www.intechopen.com manufacturing process (Zhao et al, 2003). However, the method is always applied to modify flat-sheet membrane; it is difficult to modify hollow fiber membranes, especially to modify the internal surface of hollow fiber membrane.…”

Section: Photo-induced Surface Graftingmentioning

confidence: 99%

Polyethersulfone Hollow Fiber Membranes for Hemodialysis

Su¹,

Sun²,

Zhao³

2011

Progress in Hemodialysis - From Emergent Biotechnology to Clinical Practice

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“…This was attributed to electrostatic repulsion between SO 3 -and COO -groups on heparin and negatively charged proteins in normal blood circumstance (pH 7.4). An alternative approach to membrane surface modification is protein immobilization on the hemodialysis membranes [38,39]. Zhao et al modified polysulfone membranes by immobilizing single-strand DNA onto their surfaces with UV-irradiation.…”

Section: Introductionmentioning

confidence: 99%

“…Although hydrophilicity of the DNA immobilized membranes increased significantly, amount of model protein, bovine serum albumin, adsorbed on the membranes did not decrease. This was explained by strong hydrogen bonds formed between DNA and BSA molecules [38]. Liu et al covalently immobilized plasma proteins onto polyacrylonitrile membranes to evaluate the hemocompatibility and anaphylatoxin formation [39].…”

Section: Introductionmentioning

confidence: 99%

The effects of urease immobilization on the transport characteristics and protein adsorption capacity of cellulose acetate based hemodialysis membranes

Mahlicli

Altınkaya

2009

J Mater Sci: Mater Med

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In this study, cellulose acetate (CA) based hemodialysis membranes were prepared by a dry phase inversion method and the influences of urease immobilization on the clearing performance and protein adsorption capacity of the membranes were investigated. Permeation experiments have shown that modification of CA membranes with urease immobilization not only enhanced the transport rate of urea but also increased the permeation coefficients of uric acid and creatinine by changing the structure of the membrane. Furthermore, the protein adsorption capacity of the CA membranes decreased. On the other hand, the mechanical strength of the modified CA membrane did not change significantly compared with that of the unmodified one. A mathematical model was derived to determine the rate of mass transfer of urea through modified CA membranes. Model predictions along with the experimental data suggest that urease immobilization can be used as an alternative method in preparing CA based hemodialysis membranes with improved transport characteristics and biocompatibility through reduced protein adsorption capacities.

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Surface characterization of polysulfone membranes modified by DNA immobilization

Cited by 65 publications

References 28 publications

DNA-Modified Polysulphone Microspheres for Endocrine Disruptors and Heavy Metal Ions Removal

DNA-Modified Polysulphone Microspheres for Endocrine Disruptors and Heavy Metal Ions Removal

Polyethersulfone Hollow Fiber Membranes for Hemodialysis

The effects of urease immobilization on the transport characteristics and protein adsorption capacity of cellulose acetate based hemodialysis membranes

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