In the field of histopathology, it has been observed that most images are of poor quality as a result of inadequate luminance and contrast. The first step in identifying and analyzing them is to enhance their quality while maintaining their inherent characteristics. This paper presents a novel method for enhancing histopathology images' important features, brightness preservation, and contrast by utilizing the adaptive intensity transformation gamma function in the wavelet domain. The RGB histopathological color image is first converted to the HSV color model. The V component is then stretched in order to compensate for any color distortion. In the proposed scheme, the stretched V component is split into four sub‐bands using discrete wavelet transform (DWT). Next, it determines the optimal value of the gamma correction function in the DWT lower sub‐band. A correction factor is applied using the singular value decomposition (SVD) technique to determine the optimal gamma function value using the nature‐inspired particle swarm optimization method (NIPSO). The corrected LL sub‐band is then applied to the inverse DWT (IDWT) together with the other unprocessed sub‐bands. In addition, the contrast of each feature is enhanced by employing an adaptive histogram equalization model that is contrast‐limited. The proposed method was evaluated through experiments and validations on a variety of histopathology images retrieved from multiple databases. Several quantitative studies have demonstrated that the proposed method outperforms existing enhancement techniques in terms of entropy, edge preservation index, contrast ratio, and Universal Image Quality Index (UIQI). This proposed technique increases contrast, while preserving the inherent characteristics of the original image, resulting in better quality histopathology images that can be used in disease diagnosis and inspection.