Surface degradation of composite resins by acidic medicines and ph-cycling

Valinoti, Ana Carolina; Neves, Beatriz Gonçalves; Silva, Eduardo Moreira da; Maia, Lucianne Cople

doi:10.1590/s1678-77572008000400006

Cited by 93 publications

(82 citation statements)

References 27 publications

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“…Other in vitro studies observed the erosive effects of some medicines, such as antiasthmatic syrups (9), iron supplements (4,6), antiallergic/expectorant medications (5,6,8) and reported enamel surface roughness, microhardness and morphological alteration findings (9). The erosive potential of ferrous sulfate hypothesized by Passos et al (25), was confirmed in the present research.…”

Section: Discussionsupporting

confidence: 85%

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In Vitro Erosive Effect of Pediatric Medicines on Deciduous Tooth Enamel

et al. 2014

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This study evaluated, in vitro, the erosive potential of pediatric liquid medicines in primary tooth enamel, depending on the exposure time. Sixty deciduous incisors were randomly assigned to 4 groups (n=15), according to the immersion solutions: guaifenesin; ferrous sulfate; salbutamol sulfate and artificial saliva. The immersion cycles in the medicines were undertaken under a 1-min agitation, which wasperformed three times daily, during 28 days. Surface microhardness was measured at 7,14, 21 and 28 days. The titratable acidity and buffering capacity of the immersion media were determined. Data were analyzed by Analysis of Variance and Tukey's test (α=0.05). Salbutamol sulfate caused a gradual loss in enamel microhardness deciduous, observed at all times (p<0.005). Exposure to guaifenesin or ferrous sulfate resulted in significant decrease of enamel microhardness only after 28 days (p<0.005). In the control group (artificial saliva), microhardness did not changed (p>0.005) at any of the studied times. Scanning Electron Microscopy (SEM) images revealed that after 28 days the surfaces clearly exhibited structural loss, which was unlike those immersed in artificial saliva. Erosion of deciduous enamel was dependent on the type of medicine and exposure time.

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Section: Discussionsupporting

confidence: 85%

“…Increased acidic food and drink consumption has become the primary extrinsic source of dental erosive agents (1), although acidic medicines and behavioral factors have also been identified as extrinsic etiologic factors in dental erosion (5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

In Vitro Erosive Effect of Pediatric Medicines on Deciduous Tooth Enamel

et al. 2014

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“…The longevity of these restorations depends on their abilities to withstand the harsh conditions of the oral environment such as biodegradation [5]. Gopferich et al [6], described the degradation as a "chain scission process during which polymer chains are cleaved to form first oligomers and then monomers".…”

Section: Introductionmentioning

confidence: 99%

“…The palatability of these medicines is increased with the addition of sugars such as sucrose, glucose or fructose to foster patients' acceptability and thus compliance [12,13]. Furthermore, the pH is formulated to optimize their efficacy, and, usually acidic preparations are often necessary for drug dispersion [5,14,15]. Thus, liquid oral medicines may act as extrinsic agents causing biodegradation of resin-based materials, especially if consumed frequently [5].…”

Section: Introductionmentioning

confidence: 99%

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Surface Degradation of Resin-based Materials by Pediatric Syrup Containing Amoxicillin under Erosive Challenge

Santos

Patrocínio

Fidalgo

et al. 2017

Pesqui. bras. odontopediatria clín. integr.

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Objective: To investigate the effect of a pediatric syrup containing Amoxicillin on resin-based on the surfaces of resin-based materials under pH cycling. Material and Methods: Cylindrical samples (n=60) of a compomer (Freedom) and a microhybrid composite (TPH Spectrum) were prepared following the manufacturer's instructions. The specimens were divided into two groups and treated for 30min, twice a day, for 14 days with a pediatric syrup containing Amoxicillin, Amoxil™ 500mg/5ml (experimental group) or Distilled water (control group). During the 14 days, the samples were submitted to pH cycling (3h in demineralizing, 20h in remineralizing saliva, and 1h for treatment). The surface roughness was evaluated at baseline, on the 7 th and 14 th days of erosive challenge using a profilometer and illustrated by SEM. The data were statistically analyzed by one-way ANOVA, Tukey HSD and paired T-tests (p < 0.05). At baseline, the mean Ra TPH = mean Ra F (p > 0.05). Results: After 7 days, it was observed no erosion (p = 0.674) for THP Spectrum (0.19 Ra) and an increasing of Ra (p = 0.02) for Freedom (19.95 Ra). After 14 days, it was observed an increasing of Ra for both THP Spectrum (0.56 Ra) and for Freedom (3.44 Ra), demonstrating that the degradation was treatment and time-dependent (p < 0.001). The pediatric syrup containing Amoxicillin increased the surface roughness of the TPH Spectrum surface one and a half times (p = 0.003) and the surface roughness of Freedom was increased by more than two times (p < 0.001). SEM images showed different aspects of the surfaces of the two materials with a loss of integrity to both. Conclusion: The pediatric syrup containing Amoxicillin under pH cycling increased the roughness of the both tested resin-based restorative materials.

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ATR‐FTIR spectroscopy and μ‐EDXRF spectrometry monitoring of enamel erosion caused by medicaments used in the treatment of respiratory diseases

Gomes

Bhattacharjee

Carvalho

et al. 2017

Microscopy Res & Technique

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Medicaments essential for alleviation of diseases may sometime adversely affect dental health by eroding the enamel, owing to their acidic nature. It is therefore highly desirable to be able to detect these effects quickly and reliably. In this study, we evaluated the erosive capacity of four most commonly prescribed respiratory disease syrup medicaments on enamel using micro-energy-dispersive X-ray fluorescence spectrometry (µ-EDXRF) and attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Fifty-five enamel fragments obtained from 30 bovine teeth were treated with artificial saliva (S), acebrofilin hydrochloride (AC), ambroxol hydrochloride (AM), bromhexine hydrochloride (BR), and salbutamol sulfate (SS); by immersing in 3 mL of respective solutions for 1 min, three times a day at intervals of 1 hr, for 5 days. µ-EDXRF analysis of enamel surface did not reveal significant erosion caused by the medications. However, ATR-FTIR showed a detectable shift in the phosphate (PO ) antisymmetric stretching mode (ν ) at ∼985 cm for AM, BR, and SS, indicating erosion. Multivariate statistical analysis showed that AC, AM, SS, and BR could be classified with 70%, 80%, 100%, and 100% efficiency from S (control), further highlighting the ability of ATR-FTIR to identify degree of erosion. This suggests ATR-FTIR may be used to rapidly and nondestructively investigate erosive effects of medicaments.

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Surface degradation of composite resins by acidic medicines and ph-cycling

Cited by 93 publications

References 27 publications

In Vitro Erosive Effect of Pediatric Medicines on Deciduous Tooth Enamel

In Vitro Erosive Effect of Pediatric Medicines on Deciduous Tooth Enamel

Surface Degradation of Resin-based Materials by Pediatric Syrup Containing Amoxicillin under Erosive Challenge

ATR‐FTIR spectroscopy and μ‐EDXRF spectrometry monitoring of enamel erosion caused by medicaments used in the treatment of respiratory diseases

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