Surface-Enhanced Raman Scattering with Ag Nanoparticles Optically Trapped by a Photonic Crystal Cavity

Lin, Shiwei; Zhu, Wenqi; Jin, Yuhang; Crozier, Kenneth B.

doi:10.1021/nl304069n

Cited by 125 publications

(86 citation statements)

References 30 publications

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“…Sophisticated slotted waveguides [141,[151][152][153] as well as nanobeam cavities [140,146,150,[154][155][156][157][158][159][160] have also been implemented for analyte-specific stoichiometric studies and biomolecule micromanipulation. Extreme, sub-attomolar detection of a streptavidin protein was reported for nanoslot PhC nanolasers [139,[161][162][163][164][165][166][167][168], while novel PhC nanocavities combined with plasmonic nanostructures have emerged as hybrid photonic-plasmonic biosensors [169][170][171][172][173][174][175][176][177][178][179]. Unusually sensitive biodetection down to the single-molecule level with nanostructured materials comprising selfassembled silver nanoparticles on PhC diatom biosilica [180,181] and a gold antenna-in-a-nanocavity [182] substantiates the fast and steady advancement of hybrid photonic-plasmonic instrumentation utilising PhCs.…”

Section: Photonic Crystals Engineered With Nano/microcavities For Intmentioning

confidence: 99%

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

et al. 2017

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Nanophotonic device building blocks, such as optical nano/microcavities and plasmonic nanostructures, lie at the forefront of sensing and spectrometry of trace biological and chemical substances. A new class of nanophotonic architecture has emerged by combining optically resonant dielectric nano/microcavities with plasmonically resonant metal nanostructures to enable detection at the nanoscale with extraordinary sensitivity. Initial demonstrations include single-molecule detection and even single-ion sensing. The coupled photonic-plasmonic resonator system promises a leap forward in the nanoscale analysis of physical, chemical, and biological entities. These optoplasmonic sensor structures could be the centrepiece of miniaturised analytical laboratories, on a chip, with detection capabilities that are beyond the current state of the art. In this paper, we review this burgeoning field of optoplasmonic biosensors. We first focus on the state of the art in nanoplasmonic sensor structures, high quality factor optical microcavities, and photonic crystals separately before proceeding to an outline of the most recent advances in hybrid sensor systems. We discuss the physics of this modality in brief and each of its underlying parts, then the prospects as well as challenges when integrating dielectric nano/microcavities with metal nanostructures. In Section 5, we hint to possible future applications of optoplasmonic sensing platforms which offer many degrees of freedom towards biomedical diagnostics at the level of single molecules.

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Section: Photonic Crystals Engineered With Nano/microcavities For Intmentioning

confidence: 99%

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

et al. 2017

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“…It has been shown that the mechanical vibrations can be sustained in a liquid core optical ring resonator, a liquid filled capillary that enables the determination of the mechanical properties of a sample, such as viscosity, which can change for example by the amount of dissolved glucose [18]. First steps towards adding Raman spectroscopy to microcavity biosensing were taken recently: trapped particles on a ring resonator were utilized to enhance and collect the Raman signal of a model analyte [63]. Furthermore, the trapping of nanoparticles can find utility in size spectroscopy of particles, and enhancing measurement signals [64][65][66][67].…”

Section: Biodetection Mechanismsmentioning

confidence: 99%

Taking detection to the limit with optical microcavities: Recent advances presented at the 560. WE Heraeus Seminar

Vollmer

Schwefel

2014

Eur. Phys. J. Spec. Top.

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“…Dark field microscopy is a useful tool for NP sensing, but with contrast that decreases as 1/r 6 of the NP [9,34], and is not able to discriminate scattering centers that are not nanoparticles [8]. Contrast for sensing NPs can be enhanced when their absorption spectra can be coupled to dielectric high quality-factor (Q-factor) resonators [35][36][37] or moderate Q-factor nanostructured surfaces [38].…”

Section: Introductionmentioning

confidence: 99%

Detection and Digital Resolution Counting of Nanoparticles with Optical Resonators and Applications in Biosensing

Aguirre

Long

et al. 2018

Chemosensors

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Abstract:The interaction between nanoparticles and the electromagnetic fields associated with optical nanostructures enables sensing with single-nanoparticle limits of detection and digital resolution counting of captured nanoparticles through their intrinsic dielectric permittivity, absorption, and scattering. This paper will review the fundamental sensing methods, device structures, and detection instruments that have demonstrated the capability to observe the binding and interaction of nanoparticles at the single-unit level, where the nanoparticles are comprised of biomaterial (in the case of a virus or liposome), metal (plasmonic and magnetic nanomaterials), or inorganic dielectric material (such as TiO 2 or SiN). We classify sensing approaches based upon their ability to observe single-nanoparticle attachment/detachment events that occur in a specific location, versus approaches that are capable of generating images of nanoparticle attachment on a nanostructured surface. We describe applications that include study of biomolecular interactions, viral load monitoring, and enzyme-free detection of biomolecules in a test sample in the context of in vitro diagnostics.

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Surface-Enhanced Raman Scattering with Ag Nanoparticles Optically Trapped by a Photonic Crystal Cavity

Cited by 125 publications

References 30 publications

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

Taking detection to the limit with optical microcavities: Recent advances presented at the 560. WE Heraeus Seminar

Detection and Digital Resolution Counting of Nanoparticles with Optical Resonators and Applications in Biosensing

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