Surface of Textiles and the Human Skin

Abstract

A report is given on new methods of surface modification of near-skin textiles. These modifications include the use of cyclodextrins, linear carbohydrate biopolymers and inorganic/organic hybrid networks; all of them can be permanently fixed on the textile for multiple uses. Textiles finished in this way may be used as transdermal therapeutic systems after loading with pharmaceuticals or as transdermal collector systems for stabilizing and analysing sweat components or as a means to regulate the skin climate.

Developing a quick and inexpensive in vitro (non‐animal) bioassay for mascara irritation

“…This study proposes a novel method to rapidly and inexpensively assess potential ocular irritancy by mascara, through a sublethal non‐animal‐based bioassay. Previous medical‐based toxicological studies that have employed ciliates have used complex, relatively expensive, and potentially inaccurate turbidmetric or calorimetric methods to monitor cells . Here, we use direct visual counts of large, easily recognizable protozoa to assess specific growth rate in response to treatments (mascara types).…”

“…Protozoa are ideal models ; being single‐celled eukaryotic heterotrophs, they are physiologically animal‐like, but they are not animals and, therefore, not subject to concerns associated with animal testing. Among protozoa, ciliates are the most frequently employed taxa in toxicological studies, undoubtedly as they represent good animal and human models for a range of toxins , including those associated with skin compatibility of textiles . To date, swimming patterns of the model ciliate Tetrahymena thermophila have been used to assess ocular irritancy .…”

Upper-rim alternately tethered α-cyclodextrin molecular receptors: synthesis, metal complexation and interfacial behavior

“…These results indicate a more upright orientation of the molecules in the latter case. The overall properties of the film formed with the podand 6 indicate its higher suitability for depositing high density, homogeneous supramolecular films [27][28][29][30] on solid surfaces compared to the hexapod derivative. The results obtained previously with the hexapod indicate that NaCl present in the subphase would not modify the optical properties of the transferred film.…”