“…Ingle et al 4 showed that metallic nanoparticles (NPs) had a broad-spectrum antimicrobial activity due to their small size and high surface to volume ratio. Further, many NP types, such as silver, 5 copper iodide, 6 and titanium dioxide, 7 interacting with the bacterial cell membrane can inactivate bacterial cells and norovirus surrogates causing release of intracellular substances and cell death, 8 crippling the viral capsid possibly by denaturing its proteins. Few reports are available on antiviral activity of copper nanoparticles, which confirms that copper nanoparticles also possess promising antiviral activity.…”