Surgical anatomy of innervation of the gallbladder in humans and<i>Suncus murinus</i>with special reference to morphological understanding of gallstone formation after gastrectomy

Yi, Shuang-Qin; Ohta, Tetsuo; Tsuchida, Akihiko; Terayama, Hayato; Naito, Makoto; Li, Jun; Wang, Hengxiao; Yi, Nozomi; Tanaka, Shigenori; Itoh, Masahiro

doi:10.3748/wjg.v13.i14.2066

Cited by 63 publications

(58 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Damage of the nerve fiber that innervated the gallbladder in the hepatoduodenal ligament may be the underlying mechanism for this phenomenon [6]. However, the extent and detail of lymph node dissection done for the patients were not available in our database.…”

Section: Discussionmentioning

confidence: 99%

“…The reported incident rate was usually around 10-25%, but rates as high as 47 and 60% had been cited in previous studies [3][4][5]. Possible mechanisms associated with this increased incidence included vagotomy, extent of gastrectomy, method of gastrointestinal reconstruction, and lymph node dissection [6,7]. Some authors advocated prophylactic cholecystectomy, simultaneous removal of the gallbladder during gastric resection to prevent potential gallstone-related sequelae, such as cholecystitis, cholangitis, and pancreatitis [8].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Analysis of gallstone disease after gastric cancer surgery

et al. 2017

View full text Add to dashboard Cite

Background The incidence rate of newly developed gallstone disease after gastrectomy for gastric cancer is thought to be higher than that in the general population. However, the presentation and management of these gallstones remain under debate, and the role of prophylactic cholecystectomy remains questionable. Methods Data on adult patients who were diagnosed with gastric cancer and received gastrectomy between 2000 and 2011 were extracted from the Taiwan National Health Insurance Research Database. A patient was excluded if he or she had gallstone disease or received cholecystectomy before the index date. The incidence of newly developed gallstone disease and its subsequent management were recorded. Data were analyzed to evaluate the factors associated with gallstone development and treatment options. Results A total of 17,325 gastric cancer patients who underwent gastrectomy were eligible for analysis. During the follow-up period (mean 4.1 years; median, 2.9 years), 1280 (7.4%) patients developed gallstone disease and 560 (3.2%) patients subsequently underwent cholecystectomy. The in-hospital mortality for cholecystectomy was 1.8% (10/560). Development of gallstone disease was associated with older age, total gastrectomy, duodenal exclusion, diabetes, cirrhosis, and more comorbidities. Factors associated with the use of cholecystectomy to treat gallstone disease included younger age, fewer comorbidities, medical center admission, and presentation as cholecystitis. Conclusions Although few patients required further gallbladder removal after gastrectomy for gastric malignancy, the increased mortality rate for subsequent cholecystectomy was worth noting. The decision to undergo prophylactic cholecystectomy might be individualized based upon patient characteristics and the surgeon's discretion.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Analysis of gallstone disease after gastric cancer surgery

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Many studies reported a three-four fold increased incidence 5 years after gastric surgery (up to 15-25 %) [1][2][3][4][5][6] with an estimated mean value of 17 % in all studies [1][2][3][4][5][6][7]. The underlying mechanism was thought to be related to surgical dissection of the vagus nerve branches and the anatomical gastrointestinal reconstruction [5,[8][9][10], and to the extent of gastrectomy and lymphadenectomy [1,4,[11][12][13].…”

Section: Introductionmentioning

confidence: 99%

The Cholegas Study: safety of prophylactic cholecystectomy during gastrectomy for cancer: preliminary results of a multicentric randomized clinical trial

et al. 2012

View full text Add to dashboard Cite

Background Cholelithiasis is more frequent in patients after gastrectomy, due to dissection of vagal branches and gastrointestinal reconstruction. Methods A randomized controlled trial was conducted from November 2008 to March 2012. Patients were randomized into two groups: prophylactic cholecystectomy (PC) and standard gastric surgery only (SS) for curable cancers. We planned three end points: evaluation of the number of patients who developed symptoms and needed further surgery for cholelithiasis after standard gastric cancer surgery, evaluation of the incidence of cholelithiasis overall after standard gastric cancer surgery and perioperative complications or costs of prophylactic cholecystectomy. The present study answers to the last end point only.

show abstract

“…7,8,10 In our patient, however, Pheochromocytoma Manifesting Persistent Right Shoulder Pain and Hypochondralgia Right shoulder pain associated with liver diseases is well known as a representative referred pain. 15 The adrenal gland is located at retroperitoneal space and any pathological changes usually do not influence the phrenic nerve. 14 Similarly, the right shoulder pain in our case was assumed to occur as a referred pain derived from the adrenal tumor.…”

Section: Discussionmentioning

confidence: 99%

Pheochromocytoma Manifesting Persistent Right Shoulder Pain and Hypochondralgia

Hagiya

Nakamura

Terasaka

et al. 2015

J of Gen and Family Med

View full text Add to dashboard Cite

We report a 42‐year‐old female who initially complained of sub‐acute onset of right upper quadrant abdominal pain with right shoulder pain. A CT scan incidentally revealed an adrenal tumor, and a final diagnosis of pheochromocytoma was made on the basis of endocrinological examinations. Symptomatically, the pheochromocytoma in our patient mimicked a hepato‐biliary disease by presenting abdominal pain accompanying right shoulder pain that was assumed to be referred pain via the right phrenic nerve. Physicians may need to consider the possibility of pheochromocytoma in patients with abdominal symptoms.

show abstract

Surgical anatomy of innervation of the gallbladder in humans andSuncus murinuswith special reference to morphological understanding of gallstone formation after gastrectomy

Cited by 63 publications

References 34 publications

Analysis of gallstone disease after gastric cancer surgery

Analysis of gallstone disease after gastric cancer surgery

The Cholegas Study: safety of prophylactic cholecystectomy during gastrectomy for cancer: preliminary results of a multicentric randomized clinical trial

Pheochromocytoma Manifesting Persistent Right Shoulder Pain and Hypochondralgia

Contact Info

Product

Resources

About