Surgical debridement as a treatment strategy for cervicofacial actinomycosis—Literature review and case report

Balbinot, Karolyny Martins; Sousa, Naama Waléria Alves; Pinheiro, João de Jesus Viana; Ribeiro, Ana Elisa

doi:10.1016/j.ijscr.2020.06.079

Cited by 7 publications

(4 citation statements)

References 17 publications

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“…However, an additional review of the literature without excluding prosthesis revealed more cases, where Actinomyces species caused prosthetic joint infection [ 19 ]. Drug resistance is not considered a problem in actinomycosis, therefore penicillin G or amoxicillin are considered first-line drugs for the treatment of actinomycosis together with surgical debridement of abscesses [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Septic hip abscess due to Fusobacterium nucleatum and Actinomyces turicensis in an immunocompetent SARS-CoV-2 positive patient

Nia

Ungersboeck²,

Uffmann

et al. 2021

Anaerobe

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A 42-year-old man was referred to the Department of Orthopedic Surgery with pain over his right greater trochanter and signs of systemic infection. CT showed an enhanced mass in his gluteus maximus as well as gas in the biceps femoris over the underlying hip joint. Tissue biopsy yielded Fusobacterium nucleatum and Actinomyces turicensis. The patient was successfully treated for 6 weeks with amoxicillin/clavulanic acid 875mg/125mg and metronidazole 500mg.

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Section: Discussionmentioning

confidence: 99%

Septic hip abscess due to Fusobacterium nucleatum and Actinomyces turicensis in an immunocompetent SARS-CoV-2 positive patient

Nia

Ungersboeck²,

Uffmann

et al. 2021

Anaerobe

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“…The penetration of antibiotics into the lesion may be delayed by weak vessels and solid capsules. Surgical interventions such as bone necrosis removal are performed for subacute or chronic voluminous lesions [ 129 ]. The recent treatments for Actinomycosis are summarized in Table 3 .…”

Section: Actinomycesmentioning

confidence: 99%

Current Infections of the Orofacial Region: Treatment, Diagnosis, and Epidemiology

Tahmasebi

Keshvad

Alam

et al. 2023

Life

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Undoubtedly, diagnosing and managing infections is one of the most challenging issues for orofacial clinicians. As a result of the diversity of symptoms, complicated behavior, and sometimes confusing nature of these conditions, it has become increasingly difficult to diagnose and treat them. It also highlights the need to gain a deeper insight into the orofacial microbiome as we try to improve our understanding of it. In addition to changes in patients’ lifestyles, such as changes in diet, smoking habits, sexual practices, immunosuppressive conditions, and occupational exposures, there have been changes in patients’ lifestyles that complicate the issue. Recent years have seen the development of new infection treatments due to the increased knowledge about the biology and physiology of infections. This review aimed to provide a comprehensive overview of the types of infections in the mouth, including the types that viruses, fungi, or bacteria may cause. It is important to note that we searched the published literature in the Scopus, Medline, Google Scholar, and Cochran databases from 2010 to 2021 using the following keywords: “Orofacial/Oral Infections,” “Viral/Fungal/Bacterial Infections”, “Oral Microbiota” And “Oral Microflora” without limiting our search to languages and study designs. According to the evidence, the most common infections in the clinic include herpes simplex virus, human papillomavirus, Candida albicans, Aspergillus, Actinomycosis, and Streptococcus mutans. The purpose of this study is to review the new findings on characteristics, epidemiology, risk factors, clinical manifestations, diagnosis, and new treatment for these types of infectious diseases.

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“…Ein vorzeitiger Therapieabbruch sollte daher vermieden werden. Balbinot et al sehen im Debridement nekrotischen Gewebes den Vorteil der besseren lokalen Immunantwort auf die Bakterien selbst mit letztlich verkürzter antibiotischer Folgetherapie [23]. Chronische, ausgedehnte bzw.…”

Section: Therapie Und Prognoseunclassified

“…komplizierte Prozesse (z. B. Osteomyelitis) oder Patienten mit HIV-Infektion können in seltenen Fällen eine antibiotische Therapie von bis zu 12 Monaten erfordern [1,9,[22][23][24]. In den Fällen 4 und 5 waren solche Empfehlungen zur Langzeitantibiotikatherapie aufgrund der Knochenbeteiligung ausgesprochen worden.…”

Section: Therapie Und Prognoseunclassified

Zervikofaziale Aktinomykose

Brosig

Hitzenbichler

Ernst

et al. 2021

Laryngorhinootologie

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ZusammenfassungDie Aktinomykose ist eine durch grampositive, fakultativ anaerobe Bakterien verursachte Infektionskrankheit, die sich in den meisten Fällen im zervikofazialen Bereich manifestiert und oft einen dentogenen Fokus aufweist. Das klinische Bild reicht vom akuten Abszessgeschehen bis zu chronisch fistulierenden Gewebeprozessen. Eine frühzeitige Diagnose und ein angemessenes therapeutisches Vorgehen mit einer Kombination aus ausgedehnter antibiotischer Behandlung und ggf. chirurgischer Sanierung sind für einen günstigen Krankheitsverlauf entscheidend. In diesem Artikel werden 5 Fälle von Aktinomyzeteninfektionen dargestellt, welche die Vielfalt der klinischen Erscheinungsbilder, die Problematik auf dem Weg zur richtigen Diagnose und mögliche Therapieverläufe illustrieren sollen.

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Surgical debridement as a treatment strategy for cervicofacial actinomycosis—Literature review and case report

Abstract: Highlights Antibiotic therapy and surgical debridement as a form of treatment of actinomycosis. Actinomycosis does not respond well antibiotic therapy before curettage. Debridement proved to be important for the reduction of antibiotic therapy time.

Cited by 7 publications

References 17 publications

Septic hip abscess due to Fusobacterium nucleatum and Actinomyces turicensis in an immunocompetent SARS-CoV-2 positive patient

Septic hip abscess due to Fusobacterium nucleatum and Actinomyces turicensis in an immunocompetent SARS-CoV-2 positive patient

Current Infections of the Orofacial Region: Treatment, Diagnosis, and Epidemiology

Zervikofaziale Aktinomykose

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