Surgical excision and mucosal advancement flap: Treatment for refractory lichen planus of the lip

Kim, Do Hyeon; Lim, Bo Ra; Na, Ga Hye; Kim, Eun-Jung; Park, Kun

doi:10.1111/dth.12695

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…Surprisingly, after 2 years of follow-up, recurrence was not detected ( Hadiuzzaman et al., 2013 ). In addition, a subset of physicians have attempted to treat refractory EOLP with free palatal mucosa grafts ( Kim et al., 2018 ). However, the efficacy and treatment criteria for this treatment modality have not been clearly established ( Yan et al., 2017 ).…”

Section: Non-pharmacological Treatmentmentioning

confidence: 99%

What can we learn from treatments of oral lichen planus?

Wu,

Bai,

Jing

et al. 2024

Front. Cell. Infect. Microbiol.

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Oral lichen planus (OLP), a T-lymphocyte-mediated disease of the oral mucosa, has a complex pathogenesis that involves a number of factors. The disease is characterized by recurrent episodes and requires continuous follow up, and there is no curative treatment available. Erosive lichen planus, among others, has a risk of malignant transformation and requires standardized treatment to control its progression. Different clinical subtypes of oral lichen planus require appropriate treatment. Pharmacological treatments are the most widely available and have the greatest variety of options and a number of novel pharmacological treatments are presented as highlights, including JAK enzyme inhibitors. The second is photodynamic therapy, which is the leading physiological treatment. In addition, periodontal treatment and psychological treatment should not be neglected. In this review, we briefly discuss the most recent developments in therapies for oral lichen planus after summarizing the most widely used clinical treatments, aiming to provide different proposals for future clinical treatment.

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Section: Non-pharmacological Treatmentmentioning

confidence: 99%

What can we learn from treatments of oral lichen planus?

Wu,

Bai,

Jing

et al. 2024

Front. Cell. Infect. Microbiol.

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Treatment of oral lichen planus by surgical excision and acellular dermal matrix grafting: Eleven case reports and review of literature

Chen

et al. 2021

WJCC

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BACKGROUND Oral lichen planus (OLP) is a chronic inflammatory disorder, and it can affect normal oral function. The conventional treatments for OLP are not always effective, and relapse easily occurs. Therefore, treatment of OLP is difficult and challenging. In this study, we evaluated over a long period the clinical efficacy of surgical excision and acellular dermal matrix (ADM) grafting in patients with refractory OLP. CASE SUMMARY Eleven patients with refractory OLP underwent a standardized protocol of surgical excision and ADM grafting. The condition of the area of the grafted wound, the intraoperative maximum mouth opening, pain, and clinical healing were assessed at postoperative follow-up visits. All patients had a flat surgical area with similar mucosal tissue coverage and local scar formation. Patients had no irritation and pain in their mucous membranes when eating acidic and spicy food. All patients’ mouth openings returned to normal within 2-6 mo after surgery. During follow-up, none of the patients had recurrence of OLP after surgery. The longest follow-up was 11 yr and the shortest was 6 mo, and none of the patients relapsed during follow-up. CONCLUSION Surgical excision and ADM grafting could be an effective method to treat refractory OLP.

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Surgical excision and mucosal advancement flap: Treatment for refractory lichen planus of the lip

Cited by 2 publications

References 4 publications

What can we learn from treatments of oral lichen planus?

What can we learn from treatments of oral lichen planus?

Treatment of oral lichen planus by surgical excision and acellular dermal matrix grafting: Eleven case reports and review of literature

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