Surgical experience of primary salivary gland tumors of lung: A case series

Pandey, Durgatosh; Garg, Pankaj Kumar; Jakhetiya, Ashish; Pandey, Rambha; Bhoriwal, Sandeep; Nath, Devajit; Kumar, Sunil

doi:10.1016/j.ijsu.2015.06.084

Cited by 18 publications

(16 citation statements)

References 12 publications

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“…Advanced disease at the time of initial diagnosis may make complete resection difficult, especially in cases of high‐grade PMEC. Because PMEC is a type of non‐small cell lung cancer, adjuvant therapy should be administered when complete resection is not possible, although the utility of chemotherapy and radiotherapy in these cases remains controversial …”

Section: Discussionmentioning

confidence: 99%

“…Because PMEC is a type of non-small cell lung cancer, adjuvant therapy should be administered when complete resection is not possible, although the utility of chemotherapy and radiotherapy in these cases remains controversial. [5][6][7]14,17,18 We searched medical records from Tianjin Medical University General Hospital from January 2010 to April 2017 and identified a total of eight surgically resected cases of PMEC. Table 1 displays the characteristics of the eight patients and the surgical results.…”

Section: Discussionmentioning

confidence: 99%

“…first described pulmonary mucoepidermoid carcinoma (PMEC) in 1952 . It is an extremely rare malignant neoplasm of the lung that accounts for approximately 0.1–0.2% of all lung malignancies . PMEC is a salivary gland‐type tumor of the lung, deriving from the minor salivary glands of the tracheobronchial tree and has been reported to occur over an age range of 3–78 years .…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3][4] It is an extremely rare malignant neoplasm of the lung that accounts for approximately 0.1-0.2% of all lung malignancies. [3][4][5][6][7] PMEC is a salivary gland-type tumor of the lung, 5,8 deriving from the minor salivary glands of the tracheobronchial tree 9 and has been reported to occur over an age range of 3-78 years. 3,10,11 Compared to other salivary gland-type tumors of the lung, there is no gender predilection in PMEC.…”

Section: Introductionmentioning

confidence: 99%

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Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review

Guo

Liu

et al. 2017

Thoracic Cancer

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Primary pulmonary mucoepidermoid carcinoma (PMEC) is extremely rare. Herein, we report a case of a 71‐year‐old male patient with high‐grade PMEC involving the right upper lobe that was successfully resected via lobectomy. As a result of invasion into the pleural and paratracheal lymph nodes, four cycles of adjuvant chemotherapy with paclitaxel and carboplatin were administered. There were no signs of relapse during 10 months of follow‐up. Furthermore, we reviewed the literature and summarized the surgical approaches, prognostic factors, and underlying genetic mechanisms of PMEC, which will benefit clinical treatment.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review

Guo

Liu

et al. 2017

Thoracic Cancer

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“…Adenoid cystic carcinoma (ACC) is a rare cause of thoracic malignancy, more commonly associated with salivary glands in the head and neck. As a result, there is a paucity of data from multicentre trials, with treatment being unproven and fraught with uncertainty …”

Section: Introductionmentioning

confidence: 99%

Low recurrence of lung adenoid cystic carcinoma with radiotherapy and resection

Sharma

Gupta

Yaftian

et al. 2019

ANZ Journal of Surgery

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Background: Adenoid cystic carcinoma is a rare cause of thoracic malignancy, and the prognosis may depend on the extent of surgical resection and adjuvant radiotherapy. Complete resection has low rates of local recurrence but is complicated by the involvement of central airways. Adjuvant radiotherapy is frequently recommended but unproven. Methods: We describe the technicalities of radical resection and adjuvant radiotherapy using the primary endpoint of local recurrence and secondary endpoints of locoregional (mediastinal) recurrence and distant metastasis. Resections were classed as microscopically and macroscopically clear (R0) or only macroscopically clear (R1). Results: Twelve patients (eight males) diagnosed between 1999 and 2016, with an average age of 44 AE 12 years, were included. Six of these were operable (operative group), and six had non-resectable lesions (radiotherapy group). In the operative group, three had tracheal disease and three had bronchial disease. Tracheal lesions underwent excision with tracheal anastomosis (all R1 resections). Main bronchial lesions underwent complete excision via pneumonectomy (two R0 and one R1 resections). All these patients received 50-60 Gray of adjuvant radiotherapy. At an average follow-up of 6.1 AE 4.3 years, no patient had local recurrence, two had locoregional recurrence and four had distant metastasis. The radiotherapy group received 60-70 Gray as definitive therapy, and at an average follow-up of 5.4 AE 4.2 years, three had locoregional recurrence and four had distant metastasis. Conclusion: Our case series consolidates evidence that early radical resection and radiotherapy is associated with a low risk of local recurrence in patients with thoracic adenoid cystic carcinoma.

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Massive hemoptysis due to primary mucoepidermoid carcinoma of the lung in a 12-year-old

Toit-Prinsloo

Bunn

2016

Forensic Sci Med Pathol

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Surgical experience of primary salivary gland tumors of lung: A case series

Abstract: Radical surgery to achieve R'0' resection is the main stay of treatment of PSGTTL to achieve prolonged survival.

Cited by 18 publications

References 12 publications

Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review

Clinicopathological characteristics and molecular analysis of primary pulmonary mucoepidermoid carcinoma: Case report and literature review

Low recurrence of lung adenoid cystic carcinoma with radiotherapy and resection

Massive hemoptysis due to primary mucoepidermoid carcinoma of the lung in a 12-year-old

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