Surgical management of abdominal aortic aneurysm associated with polycystic kidney disease: Report of two cases

Abstract

An abdominal aortic aneurysm associated with polycystic kidney disease is a comparatively rare but quite important condition because treating this disease is difficult, especially regarding the aortic approach. We herein present two such patients who underwent a left nephrectomy followed by an aneurysmectomy which was reconstructed with a bifurcated prosthetic graft. In both cases, the left nephrectomy enabled us to obtain an adequate operative field to expose the abdominal aorta and the surgical procedures could thus all be safely completed. The left nephrectomy is therefore considered to be a preferable surgical method for treating those patients with both conditions described here.

Revascularization and rescue of a failed kidney transplant in a case of autosomal dominant polycystic kidney disease

“…8 Concurrent AAA is reported in 5% to 10% of ADPKD patients. [5][6][7] The basis of this relationship is still controversial. ADPKD often leads to renal dysfunction and hypertension, and some theorize that these complications can contribute to the formation of AAA.…”

“…4 Abdominal aortic aneurysm (AAA) has been associated with ADPKD, with prevalence of AAA in ADPKD patients ranging from 5% to 10%, and the two conditions can significantly complicate operative management of each other. [5][6][7] …”

Extracranial Aneurysms in 2 Patients with Autosomal Recessive Polycystic Kidney Disease

“…Other vascular abnormalities have also been described in ADPKD, including intracranial dolichoectasia [32, 33], ascending aortic aneurysms [34], and dissections of the coronary [35, 36] and vertebral [37] arteries. It has also been suggested that ADPKD patients are at higher risk for AAA [38394041], although a systematic study found no increased risk of AAA in ADPKD patients compared to healthy family members [42]. …”