Surgical Management of Dysplasia and Cancer in Inflammatory Bowel Disease

Ansell, James; Grass, Fabian; Merchea, Amit

doi:10.1016/j.suc.2019.08.006

Cited by 4 publications

(2 citation statements)

References 76 publications

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“…As the incidence of IBD has increased in China and elsewhere around the world and the course of the disease has been prolonged in recent years, the number of patients who need surgery has also increased yearly (15). Improving the diagnostic accuracy, treatment, and outcomes of IBD relies not only on the ability of gastroenterologists but also requires multidisciplinary cooperation, and particularly cooperation by pathologists, imaging specialists, and surgeons (16).…”

Section: Discussionmentioning

confidence: 99%

Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience

Wang

et al. 2021

BST

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Inflammatory bowel disease (IBD) is a group of chronic nonspecific inflammatory diseases, including Crohn's disease (CD) and ulcerative colitis (UC), whose etiology and pathogenesis have not been elucidated. Its onset may be related to dietary habits, environment, genes, infection, intestinal flora, and immune disorders. IBD is developing into a global epidemic. The highest annual incidence of UC is 24.3 cases per 100,000 population-years in Europe, with 6.3 cases per 100,000 population-years in Asia. The highest annual incidence of CD is 12.7 per 100,000 population-years in Europe, with 5.0 cases per 100,000 population years in Asia (1). As the incidence increases, so does the chance of complications and poor outcomes (2).As the level of China's economic development, diet, and lifestyle have changed and the average life expectancy of the population has increased, the number of cases of IBD has increased yearly and is approaching numbers in Europe and North America (3). The incidence of IBD in China is increasing yearly, and an indeterminate or incomplete diagnosis is often common. Although the incidence of postoperative complications and in-hospital mortality of patients with IBD has significantly decreased in recent years, a retrospective analysis of the epidemiology and surgical management of IBD in China conducted in 2016 indicated that the frequency with which patients with CD were misdiagnosed with conditions such as appendicitis before surgery was as high as 50.8%. The rate of postoperative complications in both CD and UC

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Section: Discussionmentioning

confidence: 99%

Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience

Wang

et al. 2021

BST

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“…The risk for colorectal cancer increases as time progresses and is 2%, 8% and 18% after 10, 20 and 30 years of disease [15]. Moreover, 45-50% of patients diagnosed with high grade dysplasia or non-adenoma dysplasia associated lesion or mass (DaLM) have developed colorectal cancer at the time of colectomy [16]. These data…”

Section: Discussionmentioning

confidence: 87%

Ulcerative Colitis: the Role of Elective and Emergency Surgery

Mulita

Iliopoulos

Liolis

et al. 2021

AJTES

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Inflammatory bowel disease (IBD) is a group of auto-inflammatory conditions characterized by chronic, remitting, and relapsing inflammation of the alimentary tract. It is comprised of two phenotypically different entities: Crohn’s disease, and ulcerative colitis (UC). The aim of this article is to explore the role of the general surgeon regarding the treatment of patients suffering from UC while presenting a case of a 55-year-old woman with low-differentiated colon adenocarcinoma associated with ulcerative colitis. Patients with UC have a high-risk of developing colorectal cancer. While medical treatment is commonly the initial approach to UC, surgery constitutes a major contributor in dealing with UC. Inflammatory bowel disease (IBD) is a group of auto-inflammatory conditions characterized by chronic, remitting, and relapsing inflammation of the alimentary tract. It is comprised of two phenotypically different entities: Crohn’s disease, and ulcerative colitis (UC). The aim of this article is to explore the role of the general surgeon regarding the treatment of patients suffering from UC while presenting a case of a 55-year-old woman with low-differentiated colon adenocarcinoma associated with ulcerative colitis. Patients with UC have a high-risk of developing colorectal cancer. While medical treatment is commonly the initial approach to UC, surgery constitutes a major contributor in dealing with UC. Case report. A 55-year-old female with hypertension and iron deficiency anemia presented to our emergency department with fever, diarrhea, and epigastric pain for 24 hours which was not associated with heartburn, vomiting, melena, or hematemesis. On examination, the patient’s temperature was 39oC, heart rate was 104 beats per minute, blood pressure was 108/65 and the respiratory rate was 20 breaths per minute. Her abdomen was soft, without distension, and with no evidence of palpable mass...

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Colitis-Associated Cancers

Faleck

Kelsen²

2023

Pediatric Inflammatory Bowel Disease

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Surgical Management of Dysplasia and Cancer in Inflammatory Bowel Disease

Cited by 4 publications

References 76 publications

Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience

Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience

Ulcerative Colitis: the Role of Elective and Emergency Surgery

Colitis-Associated Cancers

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