Surgical management of thyroid masses: Assessing the need for frozen section evaluation

Abstract

Of the 82 patients in this study, only one extra case of malignancy would be missed by elimination of the routine use of intraoperative frozen section. The authors conclude that the routine use of intraoperative frozen section may be unnecessary. The use of an adequate preoperative FNA together with sound clinical judgment at time of surgery can adequately guide the extent of surgical resection.

Intraoperative Frozen Section in “Suspicious for Papillary Thyroid Carcinoma” after Adoption of the Bethesda System

“…Past studies advocated iFSE for all thyroid nodules because of its high specificity rate, [15][16][17][18] while other authors have argued that iFSE offers little in the evaluation of thyroid lesions and should be recommended only in those cases in which FNA has yielded unsatisfactory material or follicular proliferation. 19,20 There is some confusion in the literature regarding the utility of iFSE for suspicious lesions. Much of this confusion is due to the lumping of suspicious for follicular lesion Hurthle cell neoplasm with suspicious for PTC.…”

Cerebellum and Ocular Motor Control

“…Another form of nystagmus typically seen in patients with cerebellar syndromes is rebound nystagmus (Lin and Young, 1999; Hashimoto et al, 2003). The nystagmus is short-lived and occurs when the eyes are returned to the central position following sustained eccentric gaze.…”

Our approach to follicular-patterned lesions of the thyroid

“…[92][93][94][95][96][97] Many sections from the tumour capsule are needed because focal invasion can be missed on a single frozen section as practical issues preclude freezing multiple areas of the nodule. Hence, invasion is not often identified on frozen sections.…”