Surgical Resection of a Massive Residual Retroperineal Mass after Chemotherapy in Non-Seminomatous Germ cell Tumor of the Testis: A Borderline Case

Buffardi, A.; Destefanis, Paolo; Lillaz, B.; Bosio, Andrea; Bisconti, A.; Maria, C. De; Carchedi, Mariateresa; Rolle, Luigi; Fontana, Dario

doi:10.5301/ru.2011.8629

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“…According to the guidelines of the European Association of Urology (March 2011) and the National Comprehension Cancer Network (NCCN 2012), in cases of non-seminomatous GCT treated with orchiectomy and chemotherapy but with residual retroperitoneal lymph nodes >1 cm, removal of the residual mass is warranted and defined as “desperation surgery” in some cases [7,8]. Of fundamental importance is radical surgery [9], with ad hoc vascular surgery procedures for caval and aortic replacement [4]. …”

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confidence: 99%

Inferior vena cava prosthetic replacement in a patient with horseshoe kidney and metastatic testicular tumor: technical considerations and review of the literature

et al. 2014

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BackgroundSeminomatous and non-seminomatous Germ Cell Tumors (GCT) of the testis are a rare cancer, with an estimated incidence of 56.3 per million white males and 10 per million black males in the United States.The association between non-seminomatous GCT and horseshoe kidney is a rare event and is seen in about 1.3% of patients requiring retroperitoneal lymph node dissection. To our knowledge, no cases have been reported in which replacement of the IVC was also necessary.Case presentationWe report the case of a 22-year-old man with horseshoe kidney and metastatic non-seminomatous germ cell tumor involving the wall of the inferior vena cava.Following post-chemotherapy retroperitonal lymph node dissection, the inferior vena cava was replaced with an expanded polytetrafluoroethylene graft.At 2-years follow-up, the patient was in good health and the graft was patent. No clinical or diagnostic signs of renal impairment or recurrence of neoplastic disease were noted.ConclusionRadical surgery is warranted in patients with non-seminomatous germ cell tumor metastasizing to the retroperitoneal lymph nodes. When vena cava replacement is required, and the situation is further complicated by horseshoe kidney, as in this case, surgical technique will rely on multidisciplinary surgical treatment planning by a team composed of urologists, vascular surgeons and oncologists.

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Section: Discussionmentioning

confidence: 99%

Inferior vena cava prosthetic replacement in a patient with horseshoe kidney and metastatic testicular tumor: technical considerations and review of the literature

et al. 2014

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Surgical Resection of a Massive Residual Retroperineal Mass after Chemotherapy in Non-Seminomatous Germ cell Tumor of the Testis: A Borderline Case

Abstract: Our experience confirms that resection of residual tumors is safe and feasible also in cases of very large abdominal disease.

Cited by 1 publication

References 9 publications

Inferior vena cava prosthetic replacement in a patient with horseshoe kidney and metastatic testicular tumor: technical considerations and review of the literature

Inferior vena cava prosthetic replacement in a patient with horseshoe kidney and metastatic testicular tumor: technical considerations and review of the literature

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