2011
DOI: 10.1111/j.1365-2133.2011.10576.x
|View full text |Cite
|
Sign up to set email alerts
|

Surgical scar remodelling after photodynamic therapy using aminolaevulinic acid or its methylester: a retrospective, blinded study of patients with field cancerization

Abstract: Surgical scar remodelling and clinical improvement may be accomplished via ALA/MAL-PDT, but may require repeated treatment sessions. Larger, prospective studies are necessary to confirm the effectiveness of PDT for this indication.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

2
30
0
2

Year Published

2014
2014
2022
2022

Publication Types

Select...
7
1

Relationship

1
7

Authors

Journals

citations
Cited by 40 publications
(34 citation statements)
references
References 16 publications
2
30
0
2
Order By: Relevance
“…There was a 95% (19/20) recurrence rate at 9-month follow-up 174. Furthermore, another study (n=21) showed improvement in post-surgical scar appearance, which directly correlated with the number of ALA/MAL-PDT sessions 175. PDT represents a promising, noninvasive treatment, but more definitive studies are required to elicit its role and the regimen required in the treatment of cicatrix.…”
Section: Other Proliferative Conditionsmentioning
confidence: 99%
“…There was a 95% (19/20) recurrence rate at 9-month follow-up 174. Furthermore, another study (n=21) showed improvement in post-surgical scar appearance, which directly correlated with the number of ALA/MAL-PDT sessions 175. PDT represents a promising, noninvasive treatment, but more definitive studies are required to elicit its role and the regimen required in the treatment of cicatrix.…”
Section: Other Proliferative Conditionsmentioning
confidence: 99%
“…Mills et al reported that PDT increased MMP1, MMP9, and TGF‐β3 production and resulted in scars with improved matrix architecture in skin . Sakamoto et al reported that surgical scar remodeling could be achieved by PDT, which indicated that PDT may be effective in the treatment of existing scars . Mendoza‐Garcia et al showed that PDT exposure was associated with decreased levels of collagen and increased levels of MMP3 and elastin in skin scars .…”
Section: Discussionmentioning
confidence: 99%
“…Silbergleit et al reported that PDT yielded significant improvement in amplitude of vibration, mucosal wave, and nonvibrating portion of the vocal folds after treatment of laryngeal malignancies . Recent dermatological studies have also indicated improved cosmetic and structural outcomes when treating skin wounds and scars using PDT …”
Section: Introductionmentioning
confidence: 99%
“…In dermatology, it is used most commonly to treat actinic keratoses, but other applications exist including acne, nonmelanoma skin cancers, and scars. [1][2][3][4][5][6] For most dermatologic applications, PDT uses topical ALA or methyl ALA in combination with blue or red light. Deeper targets such as adipose tissue and hair follicles can be targeted with intralesional PDT.…”
mentioning
confidence: 99%