Surgical strategy for non‐small cell lung cancer in octogenarians

Abstract

The early detection of the disease, hopefully in stage IA enables surgical treatment by limited resection of patients aged 80 years and over. A favourable prognosis as well as low morbidity can be anticipated in such cases.

Robotic anatomic pulmonary resection in octogenarian patients with primary lung cancer: report of seven cases

“…[16] However, age itself is not considered as an exclusion criterion for surgical treatment of NSCLC. [17] More than 10 retrospective studies exist in the literature on surgery in octogenarians. Most of these reports are from Japan, since life expectancy of 80-yearolds is 8.5 years for males and 11 years for females in Japan, demonstrating that the Japanese population is aging.…”

“…They demonstrated similar morbidity, recurrence, and disease-specific survival rates in both groups. Ikeda et al [17] proposed to perform segmentectomy in octogenarians in case of smaller lesion diameter and poorer pulmonary function tests. Contrary to this, Ito et al [7] reported that lobectomy in octogenarians was associated with significantly higher rates of overall survival and disease-specific survival.…”

Pulmonary Resection for Lung Cancer in Nonagenarians: A Report of Five Cases

“…Recent studies have shown that pulmonary resection for elderly patients was a safe and feasible treatment for lung cancer, [2][3][4][5][6][7][8][9] especially in Japan ( Table 2). According to these reports, approximately 70% of patients were stage I.…”

“…Recently, several reports from Japan have shown that surgery for lung cancer in elderly people, including octogenarians, was a safe and feasible treatment. [2][3][4][5][6][7][8][9][10] Moreover, the number of lung cancer cases in nonagenarians is expected to increase rapidly in the near future, and then physicians will have to deal with these patients. However, there have been few reports 11) about the strategy for lung cancer treatment including surgery, chemotherapy, and radiotherapy for nonagenarians.…”

A Decade of Advances in Treatment of Early-Stage Lung Cancer

“…It has been repeatedly demonstrated that elderly patients with good performance status and no comorbid conditions have similar postoperative outcomes as their younger counterparts. For example, there was no difference in 5-year survival in 133 Japanese elderly patients (age greater than 75) who underwent either lobectomy or sublobar surgery for stage I NSCLC, and also no difference in the postoperative complication rate [61, 62]. Similarly, a study in the Netherlands analyzed nearly 2,000 patients over the age of 80 who were diagnosed with stage I or II NSCLC over a period of 15 years, of whom 6% (124 patients) underwent surgical intervention.…”