Background: The greater tuberosity (GT) of the proximal humerus is the attachment point of the rotator cuff, which plays a role in the movement of the shoulder joint and is the core of the entire shoulder joint. Material and Methods: In our current study, 40 patients with isolated split GT fracture (mutch type II) from july 2017 to January 2019, which was typed by J.Mutch professor, Canada in 2014, were employed in the study. They were divided into two groups: the Modified PHILOS plate group (group A, n=20) and the Hollow Screw group (group B, n=20). The functional scores Constant‑Murley Score (CMS), American Shoulder and Elbow Surgeons (ASES), The University of California at Los Angeles shoulder rating scale (UCLA) and Visual Analogue Score (VAS) were recorded in both pre-op and post-op last follow. Results: Compared with last-follow, all shoulder scores (CMS, ASES, and UCLA) of group A was significantly better than group B (P<0.05), but VAS (P>0.05). Moreover, in post-op complications, there were one GT malunion and one shoulder pain in group A, but in group B, there were seven GT disappear (35%), three GT malunion and two patients with repeated shoulder pain. Conclusion: The Modified PHILOS plate in treating isolated split GT fracture (mutch type II) was found to be effective than hollow screw in the short term follow. However, there are still some post-op complications in both groups. Keywords : Isolated Split GT Fracture; Modified PHILOS Plate; Hollow Screw