Surgical treatment of small cell lung cancer

Results of surgery in small cell carcinoma of the lung

“…These studies were criticized for including only central tumours and for not using either tomography or mediastinoscopy in the staging. In addition, in the former, many of the patients studied would not be operable with current criteria, and the intraoperative staging did not require radical mediastinal lymphadenectomy, while in the second, stages T1-T2 N0 were specifically excluded [23,24]. In the early 1990s, two meta-analysis [25,26] confirmed that adding thoracic RT to CT significantly improved long term survival for patients with limited disease.…”

Solitary brain metastasis of an occult and stable small-cell lung cancer in a schizophrenic patient: A 3-year control

“…This is the group of patients who are most reported to benefit from a surgical addition to multimodality treatment [19]. There are also clear indications that in a small percentage of slow-growing, peripheral and resectable SCLC surgery may give unusually good results [20].…”

Cisplatin and gemcitabine induction chemotherapy followed by concurrent chemoradiotherapy or surgery for locally advanced non‐small cell lung cancer

“…Combined chemotherapy and radiotherapy has become an accepted standard for the management of patients with locally advanced unresectable non-small cell lung cancer (stage IIIB and some stage IIIA). [1][2][3] To date an optimal dosage, schedule and duration of therapy has not been determined, but better results are observed when platinum-based chemotherapy is used, 4-6 radiation dosages of 60 Gy in 6 weeks or biologically equivalent schedules are used, 7,8 and when at least some component of the radiation and chemotherapy is given concurrently. 9 In 1997 we commenced a pilot study to assess the efficacy and tolerability of induction chemotherapy with two cycles of cisplatin and gemcitabine followed by definitive local treatment for IIIA and IIIB non-small cell lung cancer.…”