Surgical wound irrigation

Ciccone, Patrick; Malament, Maxwell; Bellingham, Charles

doi:10.1016/s0090-4295(74)80064-6

Cited by 6 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After removal of duplicates, 415 records remained, 401 of which were excluded after title and abstract screening. Another nine articles were excluded after full-text assessment [11,15,16,[23][24][25][26][27][28], leaving four eligible (quasi-) RCTs [29][30][31][32].…”

Section: Study Selectionmentioning

confidence: 99%

The Role of Saline Irrigation Prior to Wound Closure in the Reduction of Surgical Site Infection: A Systematic Review and Meta-Analysis

et al. 2018

View full text Add to dashboard Cite

Section: Study Selectionmentioning

confidence: 99%

The Role of Saline Irrigation Prior to Wound Closure in the Reduction of Surgical Site Infection: A Systematic Review and Meta-Analysis

et al. 2018

View full text Add to dashboard Cite

Intra-operative wound irrigation to reduce surgical site infections after abdominal surgery: a systematic review and meta-analysis

Mueller

Loos

Haller

et al. 2015

Langenbecks Arch Surg

134

110

View full text Add to dashboard Cite

show abstract

Characterisation and Safety of Intraperitoneal Perioperative Administration of Antibacterial Agents: A Systematic Review

et al. 2017

View full text Add to dashboard Cite

Intraperitoneal drug administration applies treatment at the site of diseases with gynaecological, urological, or gastrointestinal origin. The objective of this systematic review was to investigate perioperative intraperitoneal administration of antibacterial agents to characterise the drugs used and their safety profile. A protocol was registered at PROSPERO (CRD42016038956). A systematic review was conducted and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A search was performed in PubMed and EMBASE on the 22 of April 2016. The inclusion criteria were original articles involving at least 5 patients where antibacterial agents were administered intraperitoneally during or after abdominal surgery as prophylaxis or treatment of infection. Languages were limited to English, German, Danish, Norwegian, or Swedish articles. 79 studies were included which used a total of 12 different antibacterial classes. Aminoglycosides, 1 and 2 generation cephalosporins, tetracyclines, and penicillins were most commonly administered intraperitoneally during or after surgery. The antibacterial agent was usually administered intraperitoneally as monotherapy. However, some studies administered combination regimens with heparin or with another antibacterial agent. The most frequent combination was aminoglycosides and lincosamides. In total, 43% of studies lacked information regarding adverse events. The most frequently reported adverse event was discomfort or pain during administration, especially with use of oxytetracycline. At least 12 different classes of antibacterial agents have been administered intraperitoneally during or after surgery as prophylaxis or treatment of intraabdominal infections. Intraperitoneal administration seems safe although use of oxytetracycline may cause discomfort or pain.

show abstract

Surgical wound irrigation

Cited by 6 publications

References 7 publications

The Role of Saline Irrigation Prior to Wound Closure in the Reduction of Surgical Site Infection: A Systematic Review and Meta-Analysis

The Role of Saline Irrigation Prior to Wound Closure in the Reduction of Surgical Site Infection: A Systematic Review and Meta-Analysis

Intra-operative wound irrigation to reduce surgical site infections after abdominal surgery: a systematic review and meta-analysis

Characterisation and Safety of Intraperitoneal Perioperative Administration of Antibacterial Agents: A Systematic Review

Contact Info

Product

Resources

About