Surgically treated pulmonary inflammatory pseudotumor

Abstract

We report 2 cases diagnosed as so-called pulmonary inflammatory pseudotumor. In case 1, a 28-year-old man with a slow growing 6-cm pulmonary tumor who underwent a right upper lobectomy was diagnosed with an inflammatory myofibroblastic tumor. In case 2, a 55-year-old man with chest pain and cough, who underwent open lung biopsy was diagnosed with plasma cell granuloma. Despite both diagnoses being classified as pulmonary inflammatory pseudotumors, we believe they should be classified differently.

Pulmonary Inflammatory Myofibroblastic Tumor Resected by Video-Assisted Thoracoscopic Surgery: Report of a Case

“…Most patients with IMT are asymptomatic, although some complain of a cough, bloody sputum, chest pain, or dyspnea. 1,7,[22][23][24] Although our patient consulted us because of her temporary chest pain, it was unclear if the pain was associated with the IMT. Lung adenocarcinoma could not be ruled out by the radiographic characteristics of the lesion, because spicule formation, pleural indentation, and convergence of intrapulmonary blood vessels were observed on the CT scan.…”

Inflammatory Pseudotumor of the Lung with Rapid Growth

“…Re p o r t e d Ca s e s o f I n f l a mma t o r y P s e u d o t u mo r o f t h e L u n g wi t h a P r o v e n T i (Table 1). In 4 cases, slow growth of the lesions was observed over several years (5)(6)(7)(8). In contrast, in the other 3 cases growth was observed in under a year (3,9,10 (9).…”

Inflammatory myofibroblastic tumours of the lung: a case series

“…There are several theories regarding it, most of which describe an unchecked immunologic response to a foreign/ viral antigen-antibody reaction. These pseudotumours are not limited to the lung and can grow in other organ systems such as the brain or liver (2)(3)(4)(5)(6)(7)(8)(9)(10). Because of their rarity and the limited amount of tissue that can be taken through a biopsy (which finds inflammatory cells only), these pseudotumours remain a diagnostic dilemma in any organ system for both the pathologist and the surgeon.…”