Suruç İlçesindeki (Şanlıurfa-Türkiye) Aktarlarda Satılan Şifalı Bitkiler

Yalçin, Serhan; Akan, Haşan; Çakılcıoğlu, Uğur

doi:10.47947/ijnls.932374

Cited by 7 publications

(1 citation statement)

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“…Here, we propose HE as a PS in combination with white light as a virucidal compound against HCoVs. HE is approved by the EMA for clinical uses [39], so its application for example as a hand disinfectant, would be very feasible and even more so in these times when the use of natural botanical extracts is so widespread [40]. However, hypericin alone is not yet approved by the EMA.…”

Section: Discussionmentioning

confidence: 99%

Potent Virucidal Activity In Vitro of Photodynamic Therapy with Hypericum Extract as Photosensitizer and White Light against Human Coronavirus HCoV-229E

et al. 2022

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The emergent human coronavirus SARS-CoV-2 and its high infectivity rate has highlighted the strong need for new virucidal treatments. In this sense, the use of photodynamic therapy (PDT) with white light, to take advantage of the sunlight, is a potent strategy for decreasing the virulence and pathogenicity of the virus. Here, we report the virucidal effect of PDT based on Hypericum extract (HE) in combination with white light, which exhibits an inhibitory activity of the human coronavirus HCoV-229E on hepatocarcinoma Huh-7 cells. Moreover, despite continuous exposure to white light, HE has long durability, being able to maintain the prevention of viral infection. Given its potent in vitro virucidal capacity, we propose HE in combination with white light as a promising candidate to fight against SARS-CoV-2 as a virucidal compound.

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Section: Discussionmentioning

confidence: 99%