Survey of bovine tuberculosis in Nigerian beef cattle

Abstract

Bovine tuberculosis (bTB) is a zoonotic disease caused by Mycobacterium tuberculosis complex (MTBC) that primarily affects cattle, but also other domestic and wild mammals. In Nigeria, abattoir monitoring of gross bTB lesions is the only control method being applied in all animals. This study aims to investigate tubercle bacilli infection in slaughtered cattle found with visible tuberculosis-like lesions. Lesions suggesting bTB were detected in 226 cattle during abattoir monitoring in Zamfara State, Nigeria. Tissue samples collected from the affected carcasses were subjected to Ziehl-Neelsen stain (ZN). Of the 226 carcasses with lesions, 37 (16.4%) were positive by the Ziehl-Neelsen stain (ZN), and MTBC was detected from 34 (91.9%) of the 37 ZN-positive samples. Molecular typing by region of difference (RD) deletion analysis revealed the genotype of Mycobacterium bovis, Mycobacterium caprae and Mycobacterium tuberculosis. Infection was most significantly associated with age of the animals (OR = 3.49; CI: 1.29-9.47 [p = 0.002]). The findings indicate a serious threat for health as well as for TB control in Nigeria.

Preliminary Prevalence and Risk Factors of Mycobacterium bovis in Local and Imported Breeds of Cattle and Buffaloes in Mosul city, Iraq

“…Another possible reason is that imported cattle are less resistant to TB infection than local breed [22], which can make imported cattle at high risk of infection. On the other hand, the result showed that the odds of TB were greater in female, compared to male, which is in line with what was previously reported by Worku et al (2016) [23] and Ahmad et al (2018) [24] . The stress of calving and lactation might decreasefemale immunity and makes them at high risk of infection.…”

Broad diversity of Mycobacterium tuberculosis complex strains isolated from humans and cattle in Northern Algeria suggests a zoonotic transmission cycle

“…M . caprae was previously isolated from bovine TB in Algeria and other African countries [ 25 , 26 , 38 , 45 ]. The infection of cattle by M .…”

“…Regarding M. caprae, we identified two types (SB0835 and SB1451) from cattle in two slaughterhouses. M. caprae was previously isolated from bovine TB in Algeria and other African countries [25,26,38,45]. The infection of cattle by M. caprae could be explained by the cohabitation with goats [15].…”

Molecular characterisation of the Mycobacterium bovis causing bovine tuberculosis outbreaks in Poland

“…The published epidemiological studies show that M. bovis is identified worldwide (1,3). In most cases, M. bovis is transmitted between animals in the same herd in aerosols.…”