“…Currently, physicians have many different types of dermal and subdermal fillers, such as non‐permanent, permanent, reversible or non‐reversible materials. Different classifications of fillers have been proposed, according their origin and longevity (duration) 1,2 . Although manufacturers and different publications claim that the fillers are non‐toxic and non‐immunogenic, or that complications are very uncommon, 3,4 unwanted side‐effects occur with all compounds used 1,5–7 .…”