Survival After Resection of Ampullary Carcinoma: A National Population-Based Study

Abstract

This is the largest population-based analysis of ampullary carcinoma. Resection rates and survival at the national level are lower, in general, compared with cancer center reports, which may have implications for regionalizing these procedures. Many patients surviving at least 5 years seem to be cured by surgical resection.

The Influence of Prognostic Factors and Adjuvant Chemoradiation on Survival After Pancreaticoduodenectomy for Ampullary Carcinoma

“…Published 5-year overall survival (OS) rates for ampullary carcinoma range from 38% to 68% [1][2][3][4][5][6][7] . There are less published data available for AC than for PC to assist with decisions regarding adjuvant therapy.…”

Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival

“…1 In a national population-based study from the Surveillance, Epidemiology and End Results national cancer registry of the United States, the 5-year cancer-specific survival rate was 47.3%. 1 Favorable factors include resection, negative lymph node status, the presence of well-differentiated tumors, small tumor size, negative resection margin and absence of intraoperative transfusion.…”

“…1 In a national population-based study from the Surveillance, Epidemiology and End Results national cancer registry of the United States, the 5-year cancer-specific survival rate was 47.3%. 1 Favorable factors include resection, negative lymph node status, the presence of well-differentiated tumors, small tumor size, negative resection margin and absence of intraoperative transfusion. 2,3 In our previous study, pancreatic invasion and tumor size were predictors for local recurrence, while lymph node metastasis Patients with ampullary cancer are treated as for other periampullary malignancies without pathophysiological or carcinogenetic evidence.…”

Estudo da linfadenectomia radical comparada à linfadenectomia standard no tratamento cirúrgico do adenocarcinoma da papila de Vater

“…Nodal involvement is the most important independent prognostic factor in patients with adenocarcinoma of the papilla [15][16][17][18][19][20][21] , followed by the depth of tumor infiltration [15][16][17]22 , negative margins 16,23 , histological grade 22 and the need for blood transfusion 18,22 . O' Connell et al 24 described an overall survival for patients with positive and negative lymph nodes of 21.9% and 54.1%, respectively. Recently, Sakata et al 25 examined the impact of nodal disease on survival of 62 patients with adenocarcinoma of the papilla, finding an overall survival at five years of 89% in cases without lymph node involvement, 48% in cases of involvement of one to three lymph nodes and 0% in cases of metastasis to four or more lymph nodes.…”