Survival and 2‐year outcome of extremely preterm infants

Yu, V. Y. H.; Orgill, A. A.; Bajuk, Barbara; Astbury, Jill

doi:10.1111/j.1471-0528.1984.tb04823.x

Cited by 36 publications

(10 citation statements)

References 24 publications

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“…It is therefore necessary to report outcome based on gestation rather than birth weight. 18 Our survival rates before the introduction of postnatal surfactant replacement therapy were 7% at 23 weeks, 30% at 24 weeks, 31% at 25 weeks, 55% at 26 weeks, 67% at 27 weeks, and 71% at 28 weeks. 19 Surfactant has dramatically improved survival among those born as early as 24 and 25 weeks' gestation.…”

Section: Institution-based Studiesmentioning

confidence: 73%

Developmental Outcome of Extremely Preterm Infants

Yu¹

2000

Am J Perinatol

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Institution-based studies from perinatal centers are reporting encouraging survival and developmental outcome in extremely preterm infants, but population-based studies of all such births within a geographical-defined region are necessary to examine the impact of perinatal-neonatal care on the entire community. We have reported that their perinatal mortality and severe disability rate were significantly lower in those born within perinatal centers compared with those born elsewhere. Promotion of "in utero transfer" is associated with a significant improvement in their survival and developmental outcome. Postnatal surfactant therapy, which began a decade ago, saw a doubling of the survival rate for infants born as early as 24-26 weeks, while their severe disability rate remains below 10%. Although surfactant and mechanical ventilation are expensive therapies, the resulting improvement in outcome was responsible for a reduction in the cost per additional quality-adjusted life-year gained.

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Section: Institution-based Studiesmentioning

confidence: 73%

Developmental Outcome of Extremely Preterm Infants

Yu¹

2000

Am J Perinatol

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“…We have found four studies of which have used gestational age as a framework for the analysis and presentation of mortality and morbidity (Dillon & Egan 1981;Philip cr al. 1981;Herschel et al 1982;Yu et a/. 1984).…”

mentioning

confidence: 99%

Mortality and morbidity in infants born between 20 and 28 weeks gestation

Walker

Patel

1987

BJOG

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O f 149 infants with ultrasound evidence of gestational age, born in Ninewells Hospital a t between 20 and 28 weeks gestation o v e r a 5-year period, 50 were alive at birth. O f these infants, 21 died within 1 week, a further three died within 1 month and a further t w o within 18 m o n t h s . Of the 24 survivors, 8 (33%) have significant handicap. T h e obstetric factors leading to delivery and t h e m o d e of delivery are discussed.

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“…Reports of the best mode of delivery for VLBW infants with cephalic presentation vary. Yu et al [38,39] found no differences in survival and handicap rates when contrasted by mode of delivery for infants of 23 to 28 weeks' gestation with cephalic presentation. Tejani et al [31] also found no differences in the incidence of intracranial haemorrhage in premature infants with cephalic presentation between those delivered vaginally and those delivered by caesarean section.…”

Section: Discussionmentioning

confidence: 97%

Delivery of very premature infants: does the caesarean section rate relate to mortality, morbidity, or long-term outcome?

Dietl

Arnold

Haas

et al. 1991

Arch Gynecol Obstet

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A retrospective analysis of obstetric factors influencing mortality and morbidity of very premature infants (1500 g, less than or equal to 32 weeks' gestation) was undertaken. The study included 275 such infants born in the Department of Obstetrics of the University of Tübingen during the period January 1977 to June 1987. The caesarean section rate of very preterm infants increased from 28% during the period 1977-1982 to 87% during the period 1982-1987 (P less than 0.005), accompanied by an increase in survival rate from 63% to 70%. The improvement in survival rate was statistically significant for the group with birth weight 751-1000 g (P less than 0.01). The overall mortality rate was 31% after caesarean section and 36% after vaginal delivery. Amongst the causes of death of the non-survivors, acidosis was more frequent and amniotic infection syndrome less frequent in the infants delivered vaginally than in those delivered abdominally. The proportion of children with normal development at two years of age was significantly (P less than 0.02) greater amongst those born in 1982-1987 than in those born in 1977-1981. The interpretation of these findings is by no means clear but must include the hypothesis that the increased caesarean section rate may be incidental and in no way related to the improved outcome.

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Survival and 2‐year outcome of extremely preterm infants

Cited by 36 publications

References 24 publications

Developmental Outcome of Extremely Preterm Infants

Developmental Outcome of Extremely Preterm Infants

Mortality and morbidity in infants born between 20 and 28 weeks gestation

Delivery of very premature infants: does the caesarean section rate relate to mortality, morbidity, or long-term outcome?

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