Survival of Dental Implants in Irradiated Head and Neck Cancer Patients: A Retrospective Analysis

Buddula, Aravind; Assad, Daniel; Salinas, Thomas J.; Garces, Yolanda I.; Volz, John E.; Weaver, Amy L.

doi:10.1111/j.1708-8208.2010.00307.x

Cited by 40 publications

(65 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In these studies [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32], numbers of dental implants placed in atrophic posterior maxillae ranged between 12 and 2,132 per study. In all studies [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32], implants were threaded and had rough surfaces. In 17 studies [14-17, 19-27, 29-32], implants were placed in healed sites.…”

Section: Characteristics Of Studies Includedmentioning

confidence: 99%

See 1 more Smart Citation

Role of implant diameter on long-term survival of dental implants placed in posterior maxilla: a systematic review

Javed

Romanos

2014

Clin Oral Invest

View full text Add to dashboard Cite

show abstract

Section: Characteristics Of Studies Includedmentioning

confidence: 99%

“…All studies [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] were clinical and were performed at universities and/or healthcare centers. The number of participants ranged between 10 and 731 individuals, and most of the patients were males.…”

Section: Characteristics Of Studies Includedmentioning

confidence: 99%

Role of implant diameter on long-term survival of dental implants placed in posterior maxilla: a systematic review

Javed

Romanos

2014

Clin Oral Invest

View full text Add to dashboard Cite

show abstract

“…Long-term observations of osseointegrated dental implants have indicated high survival rates [1][2][3]. However, current literature depicts that one of the future problems of a society with an increasing proportion of elderly patients will be a progressive loss of hard and soft tissue attachment around dental implants due to peri-implant infections [4].…”

Section: Introductionmentioning

confidence: 99%

Influence of gaseous ozone in peri-implantitis: bactericidal efficacy and cellular response. An in vitro study using titanium and zirconia

et al. 2011

View full text Add to dashboard Cite

Dental implants are prone to bacterial colonization which may result in bone destruction and implant loss. Treatments of peri-implant disease aim to reduce bacterial adherence while leaving the implant surface intact for attachment of bone-regenerating host cells. The aims of this study were to investigate the antimicrobial efficacy of gaseous ozone on bacteria adhered to various titanium and zirconia surfaces and to evaluate adhesion of osteoblast-like MG-63 cells to ozone-treated surfaces. Saliva-coated titanium (SLA and polished) and zirconia (acid etched and polished) disks served as substrates for the adherence of Streptococcus sanguinis DSM20068 and Porphyromonas gingivalis ATCC33277. The test specimens were treated with gaseous ozone (140 ppm; 33 mL/s) for 6 and 24 s. Bacteria were resuspended using ultrasonication, serially diluted and cultured. MG-63 cell adhesion was analyzed with reference to cell attachment, morphology, spreading, and proliferation. Surface topography as well as cell morphology of the test specimens were inspected by SEM. The highest bacterial adherence was found on titanium SLA whereas the other surfaces revealed 50-75% less adherent bacteria. P. gingivalis was eliminated by ozone from all surfaces within 24 s to below the detection limit (≥99.94% reduction). S. sanguinis was more resistant and showed the highest reduction on zirconia substrates (>90% reduction). Ozone treatment did not affect the surface structures of the test specimens and did not influence osteoblastic cell adhesion and proliferation negatively. Titanium (polished) and zirconia (acid etched and polished) had a lower colonization potential and may be suitable material for implant abutments. Gaseous ozone showed selective efficacy to reduce adherent bacteria on titanium and zirconia without affecting adhesion and proliferation of osteoblastic cells. This in vitro study may provide a solid basis for clinical studies on gaseous ozone treatment of peri-implantitis and revealed an essential base for sufficient tissue regeneration.

show abstract

“…Deterioration of the bone microstructure due to, eg, osteoporosis, radiation therapy, or systemic treatment with bisphosphonates is frequently encountered in the clinic and, with respect to maxillofacial and orthopedic surgery, might affect the survival rate of Ti implants. 6,7,44 Noble et al reported on an insufficient fit of cementless femoral prostheses, 51 while Moritz et al pointed out the possible risk of implant migration in poor bone quality. 52 Buddula et al describes a greater risk of implant failure, when placed in irradiated bone.…”

mentioning

confidence: 99%

“…52 Buddula et al describes a greater risk of implant failure, when placed in irradiated bone. 7 Prospectively, this could be relevant in terms of patients receiving irradiation due to cancer treatment. These patients are running a higher risk of implant failure, especially when the implant is placed in grafted bone.…”

mentioning

confidence: 99%

Bone regenerating effect of surface-functionalized titanium implants with sustained-release characteristics of strontium in ovariectomized rats

Offermanns¹,

Oz²,

Riede³

et al. 2016

IJN

View full text Add to dashboard Cite

Since strontium (Sr) is known for its anabolic and anticatabolic effect on bone, research has been focused on its potential impact on osseointegration. The objective of this study was to investigate the performance of nanotopographic implants with a Sr-functionalized titanium (Ti) coating (Ti–Sr–O) with respect to osseointegration in osteoporotic bone. The trial was designed to examine the effect of sustained-release characteristics of Sr in poor-quality bone. Three Ti–Sr–O groups, which differed from each other in coating thickness, Sr contents, and Sr release, were examined. These were prepared by a magnetron sputtering process and compared to uncoated grade 4 Ti. Composition, morphology, and mechanical stability of the coatings were analyzed, and Sr release data were gained from in vitro washout experiments. In vivo investigation was carried out in an osteoporotic rat model and analyzed histologically, 6 weeks and 12 weeks after implantation. Median values of bone-to-implant contact and new bone formation after 6 weeks were found to be 84.7% and 54.9% (best performing Sr group) as compared to 65.2% and 23.8% (grade 4 Ti reference), respectively. The 12-week observation period revealed 84.3% and 56.5% (best performing Sr group) and 81.3% and 39.4% (grade 4 Ti reference), respectively, for the same measurements. The increase in new bone formation was found to correlate with the amount of Sr released in vitro. The results indicate that sputtered nanostructured Ti–Sr–O coatings showed sustained release of Sr and accelerate osseointegration even in poor-quality bone, and thus, may have impact on practical applications for medical implants.

show abstract

Survival of Dental Implants in Irradiated Head and Neck Cancer Patients: A Retrospective Analysis

Abstract: Dental implants placed in irradiated bone have a greater risk for failure. Survival is significantly influenced by the location of the implant (maxilla or mandible, anterior or posterior).

Cited by 40 publications

References 22 publications

Role of implant diameter on long-term survival of dental implants placed in posterior maxilla: a systematic review

Role of implant diameter on long-term survival of dental implants placed in posterior maxilla: a systematic review

Influence of gaseous ozone in peri-implantitis: bactericidal efficacy and cellular response. An in vitro study using titanium and zirconia

Bone regenerating effect of surface-functionalized titanium implants with sustained-release characteristics of strontium in ovariectomized rats

Contact Info

Product

Resources

About